Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Atipamezole is dosed at 0.2–0.5 mg/kg IM once, 5-10 min before finishing the procedure in eastern box turtles, per 81. Fleming G. Clinical technique: chelonian shell repair. J Exot Pet Med. 2008;17:246-258. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1408 — SOURCE EDITION: Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530. Atipamezole is used in eastern box turtles for alpha-2 agonist reversal. Routes documented in eastern box turtles: IM. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 1 cited dose rule for Atipamezole in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Antisedan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.2–0.5 mg/kg | once, 5-10 min before finishing the procedure | alpha-2 agonist reversal | Weak | 81. Fleming G. Clinical technique: chelonian shell repair. J Exot Pet Med. 2008;17:246-258. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1408 — SOURCE EDITION: Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.2–0.5 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.2-0.5 mg/kg IM |
| 0.5–0.75 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.5-0.75 mg/kg IM,386 0.75 mg/kg SC |
| 0.75 | SC | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.5-0.75 mg/kg IM,386 0.75 mg/kg SC |
| 1–3 | IM | Carpenter's Exotic Animal Formulary, 6th ed |
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atipamezole dose range in eastern box turtles, with cited source references: IM 0.2–0.5 mg/kg once, 5-10 min before finishing the procedure. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Atipamezole in eastern box turtles: IM.
Atipamezole is indicated in eastern box turtles for: alpha-2 agonist reversal.
These are general warnings for Atipamezole across species; consult the eastern box turtle dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 1-3 mg/kg IM |
| 0.2–0.5 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 0.2-0.5 mg/kg IM81 Chelonians/shell repair 5-10 min before finished |
| 0.5–0.75 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 0.5-0.75 mg/kg IM,275 0.75 mg/kg SC210 Chelonians |
| 0.75 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 0.5-0.75 mg/kg IM,275 0.75 mg/kg SC210 Chelonians |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.