Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Atipamezole is dosed at 0.2–0.5 mg/kg IM once, 5-10 min before finishing the procedure in eastern box turtles, per 81. Fleming G. Clinical technique: chelonian shell repair. J Exot Pet Med. 2008;17:246-258. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1408 (2026-08-01, PENDING REVIEW). Atipamezole is used in eastern box turtles for alpha-2 agonist reversal. Routes documented in eastern box turtles: IM. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 1 cited dose rule for Atipamezole in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Antisedan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.2–0.5 mg/kg | once, 5-10 min before finishing the procedure | alpha-2 agonist reversal | Weak | 81. Fleming G. Clinical technique: chelonian shell repair. J Exot Pet Med. 2008;17:246-258. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1408 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atipamezole dose range in eastern box turtles, with cited source references: IM 0.2–0.5 mg/kg once, 5-10 min before finishing the procedure. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Atipamezole in eastern box turtles: IM.
Atipamezole is indicated in eastern box turtles for: alpha-2 agonist reversal.
These are general warnings for Atipamezole across species; consult the eastern box turtle dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.