Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Vitamin K1 is dosed at 0.25–0.5 mg/kg IM not stated in eastern box turtles, per 99. Gibbons PM, Klaphake E, Carpenter JW. Reptiles. In: Carpenter JW, ed. Exotic Animal Formulary. 4th ed. St. Louis: Elsevier; 2013:83-182. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1419 (2026-08-01, PENDING REVIEW). Vitamin K1 is used in eastern box turtles for hypovitaminosis K1; coagulopathies. Routes documented in eastern box turtles: IM. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 1 cited dose rule for Vitamin K1 in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Mephyton, AquaMEPHYTON, Veta-K1
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.25–0.5 mg/kg | not stated | hypovitaminosis K1; coagulopathies | Weak | 99. Gibbons PM, Klaphake E, Carpenter JW. Reptiles. In: Carpenter JW, ed. Exotic Animal Formulary. 4th ed. St. Louis: Elsevier; 2013:83-182. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1419 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Essential cofactor for hepatic carboxylation of clotting factors II, VII, IX, X. Reverses vitamin K-dependent coagulopathy from anticoagulant rodenticides.
Give PO with fatty food (fat-soluble). SC preferred over IM (hematoma risk) or IV (anaphylaxis risk). Long-acting rodenticides (brodifacoum) require 4-6 weeks treatment. Monitor PT.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Vitamin K1 dose range in eastern box turtles, with cited source references: IM 0.25–0.5 mg/kg not stated. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Vitamin K1 in eastern box turtles: IM.
Vitamin K1 is indicated in eastern box turtles for: hypovitaminosis K1; coagulopathies.
These are general warnings for Vitamin K1 across species; consult the eastern box turtle dosing table above for species-specific guidance. Give PO with fatty food (fat-soluble). SC preferred over IM (hematoma risk) or IV (anaphylaxis risk). Long-acting rodenticides (brodifacoum) require 4-6 weeks treatment. Monitor PT.
Why a species-specific page? Vitamin K1 pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.