Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Vitamin K1 is dosed at 0.25–0.5 mg/kg IM not stated in eastern box turtles, per 99. Gibbons PM, Klaphake E, Carpenter JW. Reptiles. In: Carpenter JW, ed. Exotic Animal Formulary. 4th ed. St. Louis: Elsevier; 2013:83-182. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, printed p.1209 (Table 127.8) [w3r2 2026-08-14 - the former p.1419 was the PDF index of the held scan, not the printed page. Running head on that page reads CHAPTER 127 Reptile Formulary 1209. Offset +210 confirmed across six pages] — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530. Vitamin K1 is used in eastern box turtles for hypovitaminosis K1; coagulopathies. Routes documented in eastern box turtles: IM. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 1 cited dose rule for Vitamin K1 in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Mephyton, AquaMEPHYTON, Veta-K1
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.25–0.5 mg/kg | not stated | hypovitaminosis K1; coagulopathies | Weak | 99. Gibbons PM, Klaphake E, Carpenter JW. Reptiles. In: Carpenter JW, ed. Exotic Animal Formulary. 4th ed. St. Louis: Elsevier; 2013:83-182. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, printed p.1209 (Table 127.8) [w3r2 2026-08-14 - the former p.1419 was the PDF index of the held scan, not the printed page. Running head on that page reads CHAPTER 127 Reptile Formulary 1209. Offset +210 confirmed across six pages] — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.5 | IM | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.320 | 0.5 mg/kg i.m. q24h |
| 0.25–0.5 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 4.9 | 0.25-0.5 mg/kg IM |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Essential cofactor for hepatic carboxylation of clotting factors II, VII, IX, X. Reverses vitamin K-dependent coagulopathy from anticoagulant rodenticides.
Give PO with fatty food (fat-soluble). SC preferred over IM (hematoma risk) or IV (anaphylaxis risk). Long-acting rodenticides (brodifacoum) require 4-6 weeks treatment. Monitor PT.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Vitamin K1 dose range in eastern box turtles, with cited source references: IM 0.25–0.5 mg/kg not stated. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Vitamin K1 in eastern box turtles: IM.
Vitamin K1 is indicated in eastern box turtles for: hypovitaminosis K1; coagulopathies.
These are general warnings for Vitamin K1 across species; consult the eastern box turtle dosing table above for species-specific guidance. Give PO with fatty food (fat-soluble). SC preferred over IM (hematoma risk) or IV (anaphylaxis risk). Long-acting rodenticides (brodifacoum) require 4-6 weeks treatment. Monitor PT.
Why a species-specific page? Vitamin K1 pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.