Reptile · Testudo horsfieldii · typical adult weight 0.23–0.91 kg
Atipamezole is dosed at 0.5–0.75 mg/kg IM single dose (reversal) in russian tortoises, per 386. Raphael BL. Chelonians. In: Fowler ME, Miller RE, eds. Zoo and Wild Animal Medicine, 5th ed., Saunders/Elsevier, Philadelphia, PA; 2003:48-58. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.236 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.5 (Chemical Restraint/Anesthetic Agents Used in Reptiles.a). Atipamezole is used in russian tortoises for Alpha-2 agonist (medetomidine/dexmedetomidine) reversal. Routes documented in russian tortoises: IM. A typical adult russian tortoise weighs 0.23–0.91 kg. ExoticRx lists 1 cited dose rule for Atipamezole in russian tortoises, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Antisedan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.5–0.75 mg/kg | single dose (reversal) | Alpha-2 agonist (medetomidine/dexmedetomidine) reversal | Weak | 386. Raphael BL. Chelonians. In: Fowler ME, Miller RE, eds. Zoo and Wild Animal Medicine, 5th ed., Saunders/Elsevier, Philadelphia, PA; 2003:48-58. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.236 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.5 (Chemical Restraint/Anesthetic Agents Used in Reptiles.a).Compilation only — we have not located an independent source that prints this figure. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.2–0.5 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.2-0.5 mg/kg IM |
| 0.5–0.75 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.5-0.75 mg/kg IM,386 0.75 mg/kg SC |
| 0.75 | SC | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.5-0.75 mg/kg IM,386 0.75 mg/kg SC |
| 1–3 | IM | Carpenter's Exotic Animal Formulary, 6th ed |
Typical range: 227–907 g
If provided, volume will be calculated alongside dose.
Reference only. Verify against current literature before clinical use.
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for russian tortoises may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atipamezole dose range in russian tortoises, with cited source references: IM 0.5–0.75 mg/kg single dose (reversal). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Atipamezole in russian tortoises: IM.
Atipamezole is indicated in russian tortoises for: Alpha-2 agonist (medetomidine/dexmedetomidine) reversal.
These are general warnings for Atipamezole across species; consult the russian tortoise dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in russian tortoises — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 1-3 mg/kg IM |
| 0.2–0.5 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 0.2-0.5 mg/kg IM81 Chelonians/shell repair 5-10 min before finished |
| 0.5–0.75 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 0.5-0.75 mg/kg IM,275 0.75 mg/kg SC210 Chelonians |
| 0.75 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 0.5-0.75 mg/kg IM,275 0.75 mg/kg SC210 Chelonians |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.