Reptile · Testudo horsfieldii · typical adult weight 0.23–0.91 kg
Atipamezole is dosed at 0.5–0.75 mg/kg IM single dose (reversal) in russian tortoises, per 386. Raphael BL. Chelonians. In: Fowler ME, Miller RE, eds. Zoo and Wild Animal Medicine, 5th ed., Saunders/Elsevier, Philadelphia, PA; 2003:48-58. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.236 (2026-08-01, PENDING REVIEW). Atipamezole is used in russian tortoises for Alpha-2 agonist (medetomidine/dexmedetomidine) reversal. Routes documented in russian tortoises: IM. A typical adult russian tortoise weighs 0.23–0.91 kg. ExoticRx lists 1 cited dose rule for Atipamezole in russian tortoises, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Antisedan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.5–0.75 mg/kg | single dose (reversal) | Alpha-2 agonist (medetomidine/dexmedetomidine) reversal | Weak | 386. Raphael BL. Chelonians. In: Fowler ME, Miller RE, eds. Zoo and Wild Animal Medicine, 5th ed., Saunders/Elsevier, Philadelphia, PA; 2003:48-58. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.236 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your russian tortoise's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for russian tortoises may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atipamezole dose range in russian tortoises, with cited source references: IM 0.5–0.75 mg/kg single dose (reversal). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Atipamezole in russian tortoises: IM.
Atipamezole is indicated in russian tortoises for: Alpha-2 agonist (medetomidine/dexmedetomidine) reversal.
These are general warnings for Atipamezole across species; consult the russian tortoise dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in russian tortoises — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.