ExoticRx · exoticrx.com/drugs/flumazenil
US brand names:Romazicon
Flumazenil is dosed at 0.05 mg/kg SC 60 min after induction (if not recovered) in blue-tongue skinks, per Mans C. Sedation of pet birds. J Exot Pet Med. 2014;23:152-157. doi:10.1053/j.jepm.2014.02.009 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.239 (2026-08-01).. Verify against current literature before clinical use.
Competitive benzodiazepine receptor antagonist at GABA-A receptor. Reverses sedation, respiratory depression, and anxiolysis from benzodiazepines.
Short duration (45-60 min) — resedation risk with long-acting benzodiazepines. May precipitate seizures in benzodiazepine-dependent patients or when benzos given for seizure control.
Species references:All Blue-tongue Skink drugsAll Cat (Domestic) drugsAll Dog (Domestic) drugsAll Prairie Dog drugsAll Rabbit (Domestic) drugsAll Sugar Glider drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 6 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.01–0.02 mg/kg | IV bolus | Strong | Grimm KA, Lamont LA, Tranquilli WJ, Greene SA, Robertson SA. Veterinary Anesthesia and Analgesia: The Fifth Edition of Lumb and Jones. 5th ed. Ames, IA: Wiley-Blackwell; 2015. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.565 (2026-08-01). |
| Cat (Domestic) | IV | 0.01–0.02 mg/kg | IV bolus | Strong | Grimm KA, Lamont LA, Tranquilli WJ, Greene SA, Robertson SA. Veterinary Anesthesia and Analgesia: The Fifth Edition of Lumb and Jones. 5th ed. Ames, IA: Wiley-Blackwell; 2015. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.565 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.