Reptile · Eublepharis macularius · typical adult weight 0.04–0.10 kg
Flumazenil is dosed at 0.05 mg/kg SC once, 45 min after sedative (SC) in leopard geckos, per Doss GA, Fink DM, Sladky KK, Mans C. Comparison of subcutaneous dexmedetomidine-midazolam versus alfaxalone-midazolam sedation in leopard geckos (Eublepharis macularius). Vet Anaesth Analg. 2017;44(5):1175-1183. doi:10.1016/j.vaa.2017.03.007 https://europepmc.org/abstract/MED/28882371 — SOURCE EDITION: Exotic Animal Emergency and Critical Care Medicine — ISBN 9781119149231, https://openlibrary.org/isbn/9781119149231. Flumazenil is used in leopard geckos for Reversal of midazolam sedation. Routes documented in leopard geckos: SC. A typical adult leopard gecko weighs 0.04–0.10 kg. ExoticRx lists 1 cited dose rule for Flumazenil in leopard geckos, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Romazicon
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 0.05 mg/kg | once, 45 min after sedative (SC) | Reversal of midazolam sedation |
| Strong |
| Doss GA, Fink DM, Sladky KK, Mans C. Comparison of subcutaneous dexmedetomidine-midazolam versus alfaxalone-midazolam sedation in leopard geckos (Eublepharis macularius). Vet Anaesth Analg. 2017;44(5):1175-1183. doi:10.1016/j.vaa.2017.03.007 https://europepmc.org/abstract/MED/28882371 — SOURCE EDITION: Exotic Animal Emergency and Critical Care Medicine — ISBN 9781119149231, https://openlibrary.org/isbn/9781119149231 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.05 | IM | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.152 | 0.05 mg/kg i.m., s.c., i.v |
| 0.05 | SC | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.05 mg/kg SC, IM, IV 1 mg/20 mg of zolazepam IM, IV |
| 0.05 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 0.05 mg/kg IM, SC, IV207 1 mg/20 mg of zolazepam187 IM, IV275 All species/reversal of midazolam; extrapolated from mammals and birds Crocodilians, chelonians/reversal of zolazepam |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your leopard gecko's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Competitive benzodiazepine receptor antagonist at GABA-A receptor. Reverses sedation, respiratory depression, and anxiolysis from benzodiazepines.
Short duration (45-60 min) — resedation risk with long-acting benzodiazepines. May precipitate seizures in benzodiazepine-dependent patients or when benzos given for seizure control.
Species-specific contraindications and adverse-reaction reports for leopard geckos may differ from canine / feline reference data — consult the primary citations listed with each rule.
Flumazenil dose range in leopard geckos, with cited source references: SC 0.05 mg/kg once, 45 min after sedative (SC). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Flumazenil in leopard geckos: SC.
Flumazenil is indicated in leopard geckos for: Reversal of midazolam sedation.
These are general warnings for Flumazenil across species; consult the leopard gecko dosing table above for species-specific guidance. Short duration (45-60 min) — resedation risk with long-acting benzodiazepines. May precipitate seizures in benzodiazepine-dependent patients or when benzos given for seizure control.
Why a species-specific page? Flumazenil pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in leopard geckos — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.