Reptile · Eublepharis macularius · typical adult weight 0.04–0.10 kg
Flumazenil is dosed at 0.05 mg/kg SC once, 45 min after sedative (SC) in leopard geckos, per Doss GA, Fink DM, Sladky KK, Mans C. Comparison of subcutaneous dexmedetomidine-midazolam versus alfaxalone-midazolam sedation in leopard geckos (Eublepharis macularius). Vet Anaesth Analg. 2017;44(5):1175-1183. doi:10.1016/j.vaa.2017.03.007 https://europepmc.org/abstract/MED/28882371. Flumazenil is used in leopard geckos for Reversal of midazolam sedation. Routes documented in leopard geckos: SC. A typical adult leopard gecko weighs 0.04–0.10 kg. ExoticRx lists 1 cited dose rule for Flumazenil in leopard geckos, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Romazicon
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 0.05 mg/kg | once, 45 min after sedative (SC) | Reversal of midazolam sedation | Strong | Doss GA, Fink DM, Sladky KK, Mans C. Comparison of subcutaneous dexmedetomidine-midazolam versus alfaxalone-midazolam sedation in leopard geckos (Eublepharis macularius). Vet Anaesth Analg. 2017;44(5):1175-1183. doi:10.1016/j.vaa.2017.03.007 https://europepmc.org/abstract/MED/28882371 |
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These ranges are per kg. Enter your leopard gecko's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Competitive benzodiazepine receptor antagonist at GABA-A receptor. Reverses sedation, respiratory depression, and anxiolysis from benzodiazepines.
Short duration (45-60 min) — resedation risk with long-acting benzodiazepines. May precipitate seizures in benzodiazepine-dependent patients or when benzos given for seizure control.
Species-specific contraindications and adverse-reaction reports for leopard geckos may differ from canine / feline reference data — consult the primary citations listed with each rule.
Flumazenil dose range in leopard geckos, with cited source references: SC 0.05 mg/kg once, 45 min after sedative (SC). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Flumazenil in leopard geckos: SC.
Flumazenil is indicated in leopard geckos for: Reversal of midazolam sedation.
These are general warnings for Flumazenil across species; consult the leopard gecko dosing table above for species-specific guidance. Short duration (45-60 min) — resedation risk with long-acting benzodiazepines. May precipitate seizures in benzodiazepine-dependent patients or when benzos given for seizure control.
Why a species-specific page? Flumazenil pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in leopard geckos — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.