Reptile · Iguana iguana · typical adult weight 1.00–5.00 kg
Flumazenil is dosed at 0.05 mg/kg IM single dose as needed to reverse midazolam in green iguanas, per Bressan TF, Sobreira T, Carregaro AB. Use of rodent sedation tests to evaluate midazolam and flumazenil in green iguanas (Iguana iguana). J Am Assoc Lab Anim Sci. 2019;58(6):810-816. doi:10.30802/aalas-jaalas-19-000005 https://europepmc.org/article/MED/31645234 — CORROBORATED 2026-08-06 by independent literature: Use of Rodent Sedation Tests to Evaluate Midazolam and Flumazenil in Green Iguanas ( Iguana iguana ). (Journal of the American Association for Laboratory Animal Science : JAALAS, 2019). doi:10.30802/aalas-jaalas-19-000005. https://doi.org/10.30802/aalas-jaalas-19-000005. The paper reports this drug at this dose in this species: "used. All 10 iguanas were tested under 4 conditions, as follows: MS, midazolam (2 mg/kg IM) […]". This is a second source alongside the book already cited; it corroborates the figure and does not by itself establish that the dose is correct.. Flumazenil is used in green iguanas for Reversal of midazolam sedation. Routes documented in green iguanas: IM. A typical adult green iguana weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Flumazenil in green iguanas, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Romazicon
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.05 mg/kg | single dose as needed to reverse midazolam | Reversal of midazolam sedation | Moderate | Bressan TF, Sobreira T, Carregaro AB. Use of rodent sedation tests to evaluate midazolam and flumazenil in green iguanas (Iguana iguana). J Am Assoc Lab Anim Sci. 2019;58(6):810-816. doi:10.30802/aalas-jaalas-19-000005 https://europepmc.org/article/MED/31645234 — CORROBORATED 2026-08-06 by independent literature: Use of Rodent Sedation Tests to Evaluate Midazolam and Flumazenil in Green Iguanas ( Iguana iguana ). (Journal of the American Association for Laboratory Animal Science : JAALAS, 2019). doi:10.30802/aalas-jaalas-19-000005. https://doi.org/10.30802/aalas-jaalas-19-000005. The paper reports this drug at this dose in this species: "used. All 10 iguanas were tested under 4 conditions, as follows: MS, midazolam (2 mg/kg IM) […]". This is a second source alongside the book already cited; it corroborates the figure and does not by itself establish that the dose is correct. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.05 | IM | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.152 | 0.05 mg/kg i.m., s.c., i.v |
| 0.05 | SC | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 0.05 mg/kg SC, IM, IV 1 mg/20 mg of zolazepam IM, IV |
| 0.05 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 0.05 mg/kg IM, SC, IV207 1 mg/20 mg of zolazepam187 IM, IV275 All species/reversal of midazolam; extrapolated from mammals and birds Crocodilians, chelonians/reversal of zolazepam |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your green iguana's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Competitive benzodiazepine receptor antagonist at GABA-A receptor. Reverses sedation, respiratory depression, and anxiolysis from benzodiazepines.
Short duration (45-60 min) — resedation risk with long-acting benzodiazepines. May precipitate seizures in benzodiazepine-dependent patients or when benzos given for seizure control.
Species-specific contraindications and adverse-reaction reports for green iguanas may differ from canine / feline reference data — consult the primary citations listed with each rule.
Flumazenil dose range in green iguanas, with cited source references: IM 0.05 mg/kg single dose as needed to reverse midazolam. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Flumazenil in green iguanas: IM.
Flumazenil is indicated in green iguanas for: Reversal of midazolam sedation.
These are general warnings for Flumazenil across species; consult the green iguana dosing table above for species-specific guidance. Short duration (45-60 min) — resedation risk with long-acting benzodiazepines. May precipitate seizures in benzodiazepine-dependent patients or when benzos given for seizure control.
Why a species-specific page? Flumazenil pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in green iguanas — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.