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Deferasirox

Exjade, Jadenu

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antidote

Routes

PO

Indications

Iron overloadIron overload (hemochromatosis)

Mechanism of Action

Oral tridentate iron chelator that binds ferric iron with high affinity, promoting fecal iron excretion.

Side effects & warnings

Nephrotoxic and hepatotoxic. Monitor renal and hepatic function. GI upset common. Limited veterinary data.

Species with Deferasirox dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Weak×1Extrapolated×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Papich Handbook of Veterinary Drugs, 5th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO10–20 mg/kgq24hWeakPapich Handbook of Veterinary Drugs, 5th Ed
Cat (Domestic)PO10–20 mg/kgq24hExtrapolatedPapich Handbook of Veterinary Drugs, 5th Ed

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