Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Hydroxocobalamin is used in dog for Cyanide poisoning (smoke inhalation). Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Hydroxocobalamin in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Cyanokit
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 70 mg/kg | Single IV infusion over 15 minutes | Single dose; may repeat once if clinical signs persist | Cyanide poisoning (smoke inhalation) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed; VECCS Guidelines |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds cyanide to form cyanocobalamin (vitamin B12), which is renally excreted. Direct chemical neutralization of cyanide without methemoglobin formation.
Causes red discoloration of skin, urine, and mucous membranes for days. Interferes with colorimetric lab tests. Very safe compared to sodium nitrite.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Hydroxocobalamin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.