Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Hydroxocobalamin is dosed at 70 mg/kg IV Single IV infusion over 15 minutes in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed; VECCS Guidelines. Hydroxocobalamin is used in dogs for Cyanide poisoning (smoke inhalation). Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Hydroxocobalamin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Cyanokit
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 70 mg/kg | Single IV infusion over 15 minutes | Single dose; may repeat once if clinical signs persist | Cyanide poisoning (smoke inhalation) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed; VECCS Guidelines |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds cyanide to form cyanocobalamin (vitamin B12), which is renally excreted. Direct chemical neutralization of cyanide without methemoglobin formation.
Causes red discoloration of skin, urine, and mucous membranes for days. Interferes with colorimetric lab tests. Very safe compared to sodium nitrite.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Hydroxocobalamin dose range in dogs, with cited source references: IV 70 mg/kg Single IV infusion over 15 minutes. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Hydroxocobalamin in dogs: IV.
Cited course lengths for Hydroxocobalamin in dogs include: Single dose; may repeat once if clinical signs persist. Duration depends on the indication — match it to the specific dose rule in the table above.
Hydroxocobalamin is indicated in dogs for: Cyanide poisoning (smoke inhalation).
These are general warnings for Hydroxocobalamin across species; consult the dog dosing table above for species-specific guidance. Causes red discoloration of skin, urine, and mucous membranes for days. Interferes with colorimetric lab tests. Very safe compared to sodium nitrite.
Why a species-specific page? Hydroxocobalamin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.