Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Ethanol (Antidotal) is dosed at 600 mg/kg IV Loading 600mg/kg IV then CRI in dogs, per Shell L. Ethylene Glycol Toxicity. Veterinary Information Network; https://www.vin.com/vin_ce/abvp/html/ethylene_glycol_toxicity.html. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.515 (2026-08-01).. Ethanol (Antidotal) is used in dogs for Ethylene glycol toxicosis (when fomepizole unavailable). Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Ethanol (Antidotal) in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Ethanol Injection USP
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 600 mg/kg | Loading 600mg/kg IV then CRI | Loading dose then CRI for 36-48 hours; maintain blood ethanol 50-100mg/dl | Ethylene glycol toxicosis (when fomepizole unavailable) | Moderate | Shell L. Ethylene Glycol Toxicity. Veterinary Information Network; https://www.vin.com/vin_ce/abvp/html/ethylene_glycol_toxicity.html. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.515 (2026-08-01). |
One of the cited rules is a continuous-rate-infusion regimen: IV 600 mg/kg Loading 600mg/kg IV then CRI. CRI regimens are delivered as a continuous infusion rather than discrete doses — verify the rate against the cited source before use.
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Competitive substrate for alcohol dehydrogenase with higher affinity than ethylene glycol or methanol, preventing formation of toxic metabolites.
Fomepizole preferred when available. Causes significant CNS depression and hypoglycemia. Requires constant rate infusion and close monitoring. ICU setting only.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ethanol (Antidotal) dose range in dogs, with cited source references: IV 600 mg/kg Loading 600mg/kg IV then CRI. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ethanol (Antidotal) in dogs: IV.
Cited course lengths for Ethanol (Antidotal) in dogs include: Loading dose then CRI for 36-48 hours; maintain blood ethanol 50-100mg/dl. Duration depends on the indication — match it to the specific dose rule in the table above.
Ethanol (Antidotal) is indicated in dogs for: Ethylene glycol toxicosis (when fomepizole unavailable).
These are general warnings for Ethanol (Antidotal) across species; consult the dog dosing table above for species-specific guidance. Fomepizole preferred when available. Causes significant CNS depression and hypoglycemia. Requires constant rate infusion and close monitoring. ICU setting only.
Why a species-specific page? Ethanol (Antidotal) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.