ExoticRx · exoticrx.com/drugs/ethanol-antidotal
Ethanol Injection USP
Competitive substrate for alcohol dehydrogenase with higher affinity than ethylene glycol or methanol, preventing formation of toxic metabolites.
Fomepizole preferred when available. Causes significant CNS depression and hypoglycemia. Requires constant rate infusion and close monitoring. ICU setting only.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Ethanol (Antidotal) CRI dose rules from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 600 mg/kgLoading 600mg/kg IV then CRI | Ethylene glycol toxicosis (when fomepizole unavailable) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed; ASPCA Toxicology |
| Cat (Domestic) | IV | 600 mg/kgLoading dose then CRI q6h for 48h | Ethylene glycol toxicosis | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Ethylene glycol toxicosis (when fomepizole unavailable)
Ethylene glycol toxicosis
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.