Pocket Pet · Cynomys ludovicianus · typical adult weight 0.70–1.68 kg
Atipamezole is dosed at 0.15 mg/kg IM not specified in prairie dogs, per Comparison of Dexmedetomidine-Ketamine-Midazolam and Isoflurane for Anesthesia of Black-tailed Prairie Dogs (Cynomys ludovicianus). J Am Assoc Lab Anim Sci (JAALAS). DOI: 10.30802/AALAS-JAALAS-18-000001; PMID: 30396377; PMCID: PMC6351049. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC6351049/. Atipamezole is used in prairie dogs for Reversal of DKM anesthesia (alpha-2 antagonist), Reversal of AKD (alfaxalone-ketamine-dexmedetomidine) anesthesia; administered 45 minutes after induction. Routes documented in prairie dogs: IM, unspecified. A typical adult prairie dog weighs 0.70–1.68 kg. ExoticRx lists 2 cited dose rules for Atipamezole in prairie dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Antisedan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.15 mg/kg | not specified | Reversal of DKM anesthesia (alpha-2 antagonist) | Weak | Comparison of Dexmedetomidine-Ketamine-Midazolam and Isoflurane for Anesthesia of Black-tailed Prairie Dogs (Cynomys ludovicianus). J Am Assoc Lab Anim Sci (JAALAS). DOI: 10.30802/AALAS-JAALAS-18-000001; PMID: 30396377; PMCID: PMC6351049. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC6351049/ |
| unspecified | 1.5 mg/kg | not specified | Reversal of AKD (alfaxalone-ketamine-dexmedetomidine) anesthesia; administered 45 minutes after induction | Weak | Anesthetic effects of alfaxalone-ketamine-midazolam and alfaxalone-ketamine-dexmedetomidine administered intramuscularly in black-tailed prairie dogs (Cynomys ludovicianus). Am J Vet Res. 2022;83(9). doi:10.2460/ajvr.21.11.0193. PMID: 35895768. URL: https://pubmed.ncbi.nlm.nih.gov/35895768/ |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.15 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 9.3 | 0.15 mg/kg IM |
| 1 | SC | Carpenter's Exotic Animal Formulary, 6th edTable 9.3 | 1 mg/kg SC |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your prairie dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for prairie dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atipamezole dose ranges in prairie dogs, with cited source references: IM 0.15 mg/kg not specified; unspecified 1.5 mg/kg not specified. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Atipamezole in prairie dogs: IM, unspecified.
Atipamezole is indicated in prairie dogs for: Reversal of DKM anesthesia (alpha-2 antagonist), Reversal of AKD (alfaxalone-ketamine-dexmedetomidine) anesthesia; administered 45 minutes after induction.
These are general warnings for Atipamezole across species; consult the prairie dog dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in prairie dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.