Atipamezole for Prairie Dogs
Pocket Pet · Cynomys ludovicianus · typical adult weight 0.70–1.68 kg
Atipamezole is dosed at 0.15 mg/kg IM not specified in prairie dogs, per Comparison of Dexmedetomidine-Ketamine-Midazolam and Isoflurane for Anesthesia of Black-tailed Prairie Dogs (Cynomys ludovicianus). J Am Assoc Lab Anim Sci (JAALAS). DOI: 10.30802/AALAS-JAALAS-18-000001; PMID: 30396377; PMCID: PMC6351049. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC6351049/. Atipamezole is used in prairie dogs for Reversal of DKM anesthesia (alpha-2 antagonist), Reversal of AKD (alfaxalone-ketamine-dexmedetomidine) anesthesia; administered 45 minutes after induction. Routes documented in prairie dogs: IM, unspecified. A typical adult prairie dog weighs 0.70–1.68 kg. ExoticRx lists 2 cited dose rules for Atipamezole in prairie dogs, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Antisedan
Dose ranges
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.15 mg/kg | not specified | Reversal of DKM anesthesia (alpha-2 antagonist) | Weak | Comparison of Dexmedetomidine-Ketamine-Midazolam and Isoflurane for Anesthesia of Black-tailed Prairie Dogs (Cynomys ludovicianus). J Am Assoc Lab Anim Sci (JAALAS). DOI: 10.30802/AALAS-JAALAS-18-000001; PMID: 30396377; PMCID: PMC6351049. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC6351049/ |
| unspecified | 1.5 mg/kg | not specified | Reversal of AKD (alfaxalone-ketamine-dexmedetomidine) anesthesia; administered 45 minutes after induction | Weak | Anesthetic effects of alfaxalone-ketamine-midazolam and alfaxalone-ketamine-dexmedetomidine administered intramuscularly in black-tailed prairie dogs (Cynomys ludovicianus). Am J Vet Res. 2022;83(9). doi:10.2460/ajvr.21.11.0193. PMID: 35895768. URL: https://pubmed.ncbi.nlm.nih.gov/35895768/ |
Need the exact dose for your patient?
These ranges are per kg. Enter your prairie dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
Side effects & warnings
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for prairie dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Frequently asked questions
What is the dose of Atipamezole for Prairie Dogs?
Atipamezole dose ranges in prairie dogs, with cited source references: IM 0.15 mg/kg not specified; unspecified 1.5 mg/kg not specified.
How is Atipamezole administered in Prairie Dogs?
Documented routes for Atipamezole in prairie dogs: IM, unspecified.
What conditions does Atipamezole treat in Prairie Dogs?
Atipamezole is indicated in prairie dogs for: Reversal of DKM anesthesia (alpha-2 antagonist), Reversal of AKD (alfaxalone-ketamine-dexmedetomidine) anesthesia; administered 45 minutes after induction.
What are the side effects of Atipamezole in Prairie Dogs?
These are general warnings for Atipamezole across species; consult the prairie dog dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Other Antidote drugs with prairie dog dosing
Atipamezole dosing in other species
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in prairie dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.