Pocket Pet · Chinchilla lanigera · typical adult weight 0.40–0.80 kg
Atipamezole is dosed at 0.15 mg/kg IM Once, 45 minutes after dexmedetomidine-ketamine in chinchillas, per Parkinson L, Mans C. Anesthetic and Postanesthetic Effects of Alfaxalone-Butorphanol Compared with Dexmedetomidine-Ketamine in Chinchillas (Chinchilla lanigera). J Am Assoc Lab Anim Sci. 2017;56(3):290-295. https://pmc.ncbi.nlm.nih.gov/articles/PMC5438922/ — CORROBORATED 2026-08-06 by independent literature: Comparison of Dexmedetomidine-Ketamine with Isoflurane for Anesthesia of Chinchillas (Chinchilla lanigera). (Journal of the American Association for Laboratory Animal Science : JAALAS, 2016). PMID:27177565. https://pubmed.ncbi.nlm.nih.gov/27177565/. The paper reports this drug at this dose in this species: "tudy, adult chinchillas (n = 8; age, 2 to 5 y) were anesthetized with a combination of […]". This is a second source alongside the book already cited; it corroborates the figure and does not by itself establish that the dose is correct.. Atipamezole is used in chinchillas for Reversal of dexmedetomidine sedation/anaesthesia, Alpha-2 agonist (medetomidine/dexmedetomidine) reversal. Routes documented in chinchillas: IM, SC. A typical adult chinchilla weighs 0.40–0.80 kg. ExoticRx lists 2 cited dose rules for Atipamezole in chinchillas, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Antisedan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.15 mg/kg | Once, 45 minutes after dexmedetomidine-ketamine | Reversal of dexmedetomidine sedation/anaesthesia | Strong | Parkinson L, Mans C. Anesthetic and Postanesthetic Effects of Alfaxalone-Butorphanol Compared with Dexmedetomidine-Ketamine in Chinchillas (Chinchilla lanigera). J Am Assoc Lab Anim Sci. 2017;56(3):290-295. https://pmc.ncbi.nlm.nih.gov/articles/PMC5438922/ — CORROBORATED 2026-08-06 by independent literature: Comparison of Dexmedetomidine-Ketamine with Isoflurane for Anesthesia of Chinchillas (Chinchilla lanigera). (Journal of the American Association for Laboratory Animal Science : JAALAS, 2016). PMID:27177565. https://pubmed.ncbi.nlm.nih.gov/27177565/. The paper reports this drug at this dose in this species: "tudy, adult chinchillas (n = 8; age, 2 to 5 y) were anesthetized with a combination of […]". This is a second source alongside the book already cited; it corroborates the figure and does not by itself establish that the dose is correct. |
| SC | 1 mg/kg | not stated in source | Alpha-2 agonist (medetomidine/dexmedetomidine) reversal | Weak | Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.783 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.3 (Chemical Restraint/Anesthetic Agents Used in Rodents). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, ; Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery — ISBN 9780323484350, |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.15 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 9.3 | 0.15 mg/kg IM |
| 1 | SC | Carpenter's Exotic Animal Formulary, 6th edTable 9.3 | 1 mg/kg SC |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for chinchillas may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atipamezole dose ranges in chinchillas, with cited source references: IM 0.15 mg/kg Once, 45 minutes after dexmedetomidine-ketamine; SC 1 mg/kg not stated in source. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Atipamezole in chinchillas: IM, SC.
Atipamezole is indicated in chinchillas for: Reversal of dexmedetomidine sedation/anaesthesia, Alpha-2 agonist (medetomidine/dexmedetomidine) reversal.
These are general warnings for Atipamezole across species; consult the chinchilla dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in chinchillas — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.