Pocket Pet · Octodon degus · typical adult weight 0.17–0.30 kg
Atipamezole is dosed at 1 mg/kg SC once (reversal) in degus, per Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.783 (2026-08-01, PENDING REVIEW). Atipamezole is used in degus for Alpha-2 agonist reversal. Routes documented in degus: SC. A typical adult degu weighs 0.17–0.30 kg. ExoticRx lists 1 cited dose rule for Atipamezole in degus, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Antisedan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 1 mg/kg | once (reversal) | Alpha-2 agonist reversal | Weak | Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.783 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your degu's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for degus may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atipamezole dose range in degus, with cited source references: SC 1 mg/kg once (reversal). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Atipamezole in degus: SC.
Atipamezole is indicated in degus for: Alpha-2 agonist reversal.
These are general warnings for Atipamezole across species; consult the degu dosing table above for species-specific guidance. IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in degus — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.