Atipamezole for Pet Rat
Pocket Pet · Rattus norvegicus var. domestica · typical adult weight 0.25–0.70 kg
Atipamezole is used in pet rat for Xylazine reversal. Routes documented in pet rat: IM. A typical adult pet rat weighs 0.25–0.70 kg. ExoticRx lists 1 cited dose rule for Atipamezole in pet rat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Antisedan
Dose ranges
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 0.5–1 mg/kg | Once | Xylazine reversal | Moderate | Carpenter 6e |
Need the exact dose for your patient?
These ranges are per kg. Enter your pet rat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Selective alpha-2 adrenergic antagonist. Specifically reverses sedation, bradycardia, and other effects of medetomidine/dexmedetomidine.
Side effects & warnings
IM route only (IV can cause cardiovascular excitation). Give equal volume to medetomidine or 5x volume of dexmedetomidine. Reversal within 5-10 minutes. May unmask pain.
Species-specific contraindications and adverse-reaction reports for pet rat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atipamezole dosing in other species
Why a species-specific page? Atipamezole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in pet rat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.