ExoticRx · exoticrx.com/drugs/edrophonium
US brand names:Tensilon, Enlon
Edrophonium is dosed at 0.1–0.2 mg/kg IV Single IV test dose in dogs, per Lipsitz D. Chapter 74: Diseases of the Neuromuscular Junction. In: Bruyette DS, ed. Clinical Small Animal Internal Medicine. John Wiley & Sons, Inc.; 2020. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.468 (2026-08-01).. Verify against current literature before clinical use.
Ultra-short-acting reversible acetylcholinesterase inhibitor used diagnostically. Transient improvement in myasthenia gravis confirms the diagnosis.
Very short duration (5-10 minutes). Have atropine ready for cholinergic reactions. False negatives possible. Use IV only with monitoring.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.1–0.2 mg/kg | Single IV test dose | Strong | Lipsitz D. Chapter 74: Diseases of the Neuromuscular Junction. In: Bruyette DS, ed. Clinical Small Animal Internal Medicine. John Wiley & Sons, Inc.; 2020. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.468 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.