Cat · Felis catus · typical adult weight 2.50–7.00 kg
Physostigmine is used in cat for Anticholinergic toxicity. Routes documented in cat: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Physostigmine in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Antilirium
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.01–0.02 mg/kg | Slow IV push; may repeat q15-30min | Short acting; titrate to effect | Anticholinergic toxicity | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
Absolute dose ceiling, regardless of body weight: 1 mg total (IV).
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Reversible carbamate acetylcholinesterase inhibitor that crosses the blood-brain barrier, reversing both central and peripheral anticholinergic toxicity.
Short duration of action — repeat dosing often needed. Can cause cholinergic crisis. Atropine must be available as counter-antidote. Slow IV push only.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Physostigmine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.