Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Vitamin K1 is used in dog for Anticoagulant rodenticide poisoning. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Vitamin K1 in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Mephyton, AquaMEPHYTON, Veta-K1
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2.5–5 mg/kg | q12h | 4-6 weeks for long-acting rodenticides | Anticoagulant rodenticide poisoning | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Essential cofactor for hepatic carboxylation of clotting factors II, VII, IX, X. Reverses vitamin K-dependent coagulopathy from anticoagulant rodenticides.
Give PO with fatty food (fat-soluble). SC preferred over IM (hematoma risk) or IV (anaphylaxis risk). Long-acting rodenticides (brodifacoum) require 4-6 weeks treatment. Monitor PT.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Vitamin K1 pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.