Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Yohimbine is dosed at 0.2–1 mg/kg IM, IV not stated in source in rabbits, per GillettCS. Selected drug dosages and clinical reference data. In: Manning PJ, Ringler DH, Newcomer CE, eds. The Biology of the Laboratory Rabbit, 2nd ed., Academic Press, San Diego, CA; 1994:467-472. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.865 (2026-08-01, PENDING REVIEW). Yohimbine is used in rabbits for Alpha2-adrenergic antagonist; xylazine reversal. Routes documented in rabbits: IM, IV. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Yohimbine in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Yobine
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM, IV | 0.2–1 mg/kg | not stated in source | Alpha2-adrenergic antagonist; xylazine reversal | Moderate | GillettCS. Selected drug dosages and clinical reference data. In: Manning PJ, Ringler DH, Newcomer CE, eds. The Biology of the Laboratory Rabbit, 2nd ed., Academic Press, San Diego, CA; 1994:467-472. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.865 (2026-08-01, PENDING REVIEW) |
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Alpha-2 adrenergic antagonist reversing sedation from xylazine and other alpha-2 agonists. Less selective than atipamezole.
Primarily used to reverse xylazine sedation. Less selective than atipamezole (also blocks alpha-1). Tremors, excitation, seizures at high doses. IV route preferred.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Yohimbine dose range in rabbits, with cited source references: IM, IV 0.2–1 mg/kg not stated in source. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Yohimbine in rabbits: IM, IV.
Yohimbine is indicated in rabbits for: Alpha2-adrenergic antagonist; xylazine reversal.
These are general warnings for Yohimbine across species; consult the rabbit dosing table above for species-specific guidance. Primarily used to reverse xylazine sedation. Less selective than atipamezole (also blocks alpha-1). Tremors, excitation, seizures at high doses. IV route preferred.
Why a species-specific page? Yohimbine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.