ExoticRx · exoticrx.com/drugs/yohimbine
US brand names:Yobine
Yohimbine is dosed at 0.1–0.14 mg/kg IV IV slowly in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Alpha-2 adrenergic antagonist reversing sedation from xylazine and other alpha-2 agonists. Less selective than atipamezole.
Primarily used to reverse xylazine sedation. Less selective than atipamezole (also blocks alpha-1). Tremors, excitation, seizures at high doses. IV route preferred.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.1–0.14 mg/kg | IV slowly | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.