Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Piperazine is dosed at 100–200 mg/kg PO once, repeat in 14 days in rabbits, per Quesenberry K, Orcutt C, Mans C, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Chapter 14 'Gastrointestinal Diseases of Rabbits', p.185 (doi:10.1016/B978-0-323-48435-0.00014-9) | Carpenter's rabbit rows cite: 194. Plumb DC. Plumb's Veterinary Drug Handbook, 9th ed. — Verified against Quesenberry et al., Ferrets, Rabbits and Rodents, 4th Ed, p.197 (2026-08-01).. Piperazine is used in rabbits for Roundworm infections. Routes documented in rabbits: PO. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Piperazine in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Pipa-Tabs, Sergeants Worm Away
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 100–200 mg/kg | once, repeat in 14 days | 2 doses | Roundworm infections | Moderate | Quesenberry K, Orcutt C, Mans C, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Chapter 14 'Gastrointestinal Diseases of Rabbits', p.185 (doi:10.1016/B978-0-323-48435-0.00014-9) | Carpenter's rabbit rows cite: 194. Plumb DC. Plumb's Veterinary Drug Handbook, 9th ed. — Verified against Quesenberry et al., Ferrets, Rabbits and Rodents, 4th Ed, p.197 (2026-08-01). |
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These ranges are per kg. Enter your rabbit's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
GABA agonist that causes flaccid paralysis in ascarids (roundworms). Worms are expelled alive by peristalsis.
Only effective against ascarids (roundworms). Wide safety margin. May cause vomiting at high doses. Do not combine with pyrantel (antagonistic).
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Piperazine dose range in rabbits, with cited source references: PO 100–200 mg/kg once, repeat in 14 days. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Piperazine in rabbits: PO.
Cited course lengths for Piperazine in rabbits include: 2 doses. Duration depends on the indication — match it to the specific dose rule in the table above.
Piperazine is indicated in rabbits for: Roundworm infections.
These are general warnings for Piperazine across species; consult the rabbit dosing table above for species-specific guidance. Only effective against ascarids (roundworms). Wide safety margin. May cause vomiting at high doses. Do not combine with pyrantel (antagonistic).
Why a species-specific page? Piperazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.