ExoticRx · exoticrx.com/drugs/piperazine
US brand names:Pipa-Tabs, Sergeants Worm Away
Piperazine is dosed at 100–200 mg/kg PO once, repeat in 14 days in african grey parrots, per Doneley B. Formulary. In: Doneley B, eds. Avian Medicine and Surgery in Practice: Companion and Aviary Birds; Manson Publishing, London, UK; 2011:285-320. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.439 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 5.4 (Antiparasitic Agents Used in Birds). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Verify against current literature before clinical use.
GABA agonist that causes flaccid paralysis in ascarids (roundworms). Worms are expelled alive by peristalsis.
Only effective against ascarids (roundworms). Wide safety margin. May cause vomiting at high doses. Do not combine with pyrantel (antagonistic).
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 19 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 44–66 mg/kg | once, repeat in 14-21 days | Weak | Papich MG, Saunders Handbook of Veterinary Drugs, 4th ed, printed p.642 (corpus PDF p.670) - Piperazine, Small Animal Dosage, Dogs and Cats: '44-66 mg/kg administered once PO.' — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
| Cat (Domestic) | PO | 44–66 mg/kg | once, repeat in 14-21 days | Weak | Papich MG, Saunders Handbook of Veterinary Drugs, 4th ed, printed p.642 (corpus PDF p.670) - Piperazine, Small Animal Dosage, Dogs and Cats: '44-66 mg/kg administered once PO.' — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
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Species references:All African Clawed Frog drugsAll African Grey Parrot drugsAll Axolotl drugsAll Betta (Siamese fighting fish) drugsAll Cat (Domestic) drugsAll Chicken (Poultry) drugsAll Dog (Domestic) drugsAll Domestic Pigeon drugsAll Ferret drugsAll Fire Salamander drugsAll Goldfish drugsAll Houston Toad drugsAll Koi drugsAll Pet Rat drugsAll Rabbit (Domestic) drugsAll Sugar Glider drugsAll Syrian Hamster drugsAll White's Tree Frog drugsAll Zebra Finch drugs