Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Piperazine is dosed at 44–66 mg/kg PO once, repeat in 14-21 days in dogs, per Papich MG, Saunders Handbook of Veterinary Drugs, 4th ed, printed p.642 (corpus PDF p.670) - Piperazine, Small Animal Dosage, Dogs and Cats: '44-66 mg/kg administered once PO.'. Piperazine is used in dogs for Roundworm (Toxocara). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Piperazine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Pipa-Tabs, Sergeants Worm Away
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 44–66 mg/kg | once, repeat in 14-21 days | 2 doses | Roundworm (Toxocara) | Moderate | Papich MG, Saunders Handbook of Veterinary Drugs, 4th ed, printed p.642 (corpus PDF p.670) - Piperazine, Small Animal Dosage, Dogs and Cats: '44-66 mg/kg administered once PO.' |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
GABA agonist that causes flaccid paralysis in ascarids (roundworms). Worms are expelled alive by peristalsis.
Only effective against ascarids (roundworms). Wide safety margin. May cause vomiting at high doses. Do not combine with pyrantel (antagonistic).
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Piperazine dose range in dogs, with cited source references: PO 44–66 mg/kg once, repeat in 14-21 days. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Piperazine in dogs: PO.
Cited course lengths for Piperazine in dogs include: 2 doses. Duration depends on the indication — match it to the specific dose rule in the table above.
Piperazine is indicated in dogs for: Roundworm (Toxocara).
These are general warnings for Piperazine across species; consult the dog dosing table above for species-specific guidance. Only effective against ascarids (roundworms). Wide safety margin. May cause vomiting at high doses. Do not combine with pyrantel (antagonistic).
Why a species-specific page? Piperazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.