Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Diethylcarbamazine is dosed at 6.6 mg/kg PO q24h in dogs, per Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.264 (2026-08-01).. Diethylcarbamazine is used in dogs for Heartworm prevention. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Diethylcarbamazine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Filaribits, DEC
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 6.6 mg/kg | q24h | Year-round (daily) | Heartworm prevention | Strong | Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.264 (2026-08-01). |
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Sensitizes microfilariae to host immune attack. Exact mechanism unclear; may involve inhibition of arachidonic acid metabolism in parasites.
CONTRAINDICATED in heartworm-positive dogs (anaphylaxis from microfilaria die-off). Must test negative before starting. Daily dosing required. Largely replaced by monthly preventatives.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Diethylcarbamazine dose range in dogs, with cited source references: PO 6.6 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Diethylcarbamazine in dogs: PO.
Cited course lengths for Diethylcarbamazine in dogs include: Year-round (daily). Duration depends on the indication — match it to the specific dose rule in the table above.
Diethylcarbamazine is indicated in dogs for: Heartworm prevention.
These are general warnings for Diethylcarbamazine across species; consult the dog dosing table above for species-specific guidance. CONTRAINDICATED in heartworm-positive dogs (anaphylaxis from microfilaria die-off). Must test negative before starting. Daily dosing required. Largely replaced by monthly preventatives.
Why a species-specific page? Diethylcarbamazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.