Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Diethylcarbamazine is dosed at 6.6 mg/kg PO q24h in dogs, per Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.264 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.264' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.236; verified by finding the drug named there. If you are holding the book, turn to p.236. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Diethylcarbamazine is used in dogs for Heartworm prevention. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Diethylcarbamazine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Filaribits, DEC
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 6.6 mg/kg | q24h | Year-round (daily) | Heartworm prevention | Strong |
| Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.264 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.264' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.236; verified by finding the drug named there. If you are holding the book, turn to p.236. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 6.6 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.264 | • Heartworm prophylaxis: 6.6 mg/kg q24h PO. |
| 55–110 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.264 | • Treatment of ascarids: 55-110 mg/kg PO, as a single treatment (110 mg/kg dose |
| 110 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.264 | • Treatment of ascarids: 55-110 mg/kg PO, as a single treatment (110 mg/kg dose |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Sensitizes microfilariae to host immune attack. Exact mechanism unclear; may involve inhibition of arachidonic acid metabolism in parasites.
CONTRAINDICATED in heartworm-positive dogs (anaphylaxis from microfilaria die-off). Must test negative before starting. Daily dosing required. Largely replaced by monthly preventatives.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Diethylcarbamazine dose range in dogs, with cited source references: PO 6.6 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Diethylcarbamazine in dogs: PO.
Cited course lengths for Diethylcarbamazine in dogs include: Year-round (daily). Duration depends on the indication — match it to the specific dose rule in the table above.
Diethylcarbamazine is indicated in dogs for: Heartworm prevention.
These are general warnings for Diethylcarbamazine across species; consult the dog dosing table above for species-specific guidance. CONTRAINDICATED in heartworm-positive dogs (anaphylaxis from microfilaria die-off). Must test negative before starting. Daily dosing required. Largely replaced by monthly preventatives.
Why a species-specific page? Diethylcarbamazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.