Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Atovaquone is dosed at 13.3 mg/kg PO q8h with a fatty meal for 10 days in dogs, per Lin ECY, Chueh LL, Lin CN, Hsieh LE, Su BL. The therapeutic efficacy of two antibabesial strategies against Babesia gibsoni. Vet Parasitol. 2012;186(3-4):159-164. doi:10.1016/j.vetpar.2011.11.073 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.136 (2026-08-01). — Plumb's 10th ed (held) printed p.108, Atovaquone monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Atovaquone is used in dogs for Babesiosis (with azithromycin). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Atovaquone in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Mepron
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 13.3 mg/kg | q8h with a fatty meal for 10 days | 10 days | Babesiosis (with azithromycin) | Moderate | Lin ECY, Chueh LL, Lin CN, Hsieh LE, Su BL. The therapeutic efficacy of two antibabesial strategies against Babesia gibsoni. Vet Parasitol. 2012;186(3-4):159-164. doi:10.1016/j.vetpar.2011.11.073 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.136 (2026-08-01). — Plumb's 10th ed (held) printed p.108, Atovaquone monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 15 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.87 | • 15 mg/kg q8h, PO, in combination • 13.3 mg/kg q8h, PO for 10 days, |
| 13.3 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.87 | • 15 mg/kg q8h, PO, in combination • 13.3 mg/kg q8h, PO for 10 days, |
| 10 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.87 | with azithromycin (10 mg/kg q24h). usually in combination with azithro- |
| 10 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.87 | mycin (10 mg/kg q24h, PO). |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Inhibits mitochondrial electron transport at cytochrome bc1 complex (Complex III) in protozoa. Active against Pneumocystis, Toxoplasma, Babesia.
Must be taken with fatty food for absorption. GI upset common. Often combined with azithromycin for Babesia. Limited veterinary data.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Atovaquone dose range in dogs, with cited source references: PO 13.3 mg/kg q8h with a fatty meal for 10 days. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Atovaquone in dogs: PO.
Cited course lengths for Atovaquone in dogs include: 10 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Atovaquone is indicated in dogs for: Babesiosis (with azithromycin).
These are general warnings for Atovaquone across species; consult the dog dosing table above for species-specific guidance. Must be taken with fatty food for absorption. GI upset common. Often combined with azithromycin for Babesia. Limited veterinary data.
Why a species-specific page? Atovaquone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.