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Atovaquone for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Atovaquone is used in cat for Cytauxzoonosis. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Atovaquone in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Mepron

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO15 mg/kgq8h10 daysCytauxzoonosisWeakPlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Inhibits mitochondrial electron transport at cytochrome bc1 complex (Complex III) in protozoa. Active against Pneumocystis, Toxoplasma, Babesia.

Side effects & warnings

Must be taken with fatty food for absorption. GI upset common. Often combined with azithromycin for Babesia. Limited veterinary data.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antiparasitic drugs with cat dosing

Atovaquone dosing in other species

Why a species-specific page? Atovaquone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.