Cat · Felis catus · typical adult weight 2.50–7.00 kg
Fipronil-S-Methoprene is used in cat for Fleas and ticks. Routes documented in cat: TOPICAL. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Fipronil-S-Methoprene in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Frontline Plus
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL | 0 weight-based pipette | q30 days | Monthly | Fleas and ticks | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Fipronil blocks GABA-gated chloride channels in arthropod CNS; S-methoprene is an insect growth regulator (IGR) preventing flea egg/larval development.
Dogs and cats. Monthly topical. TOXIC to rabbits. Do not use on rabbits. Keep away from aquatic environments. Apply to dry skin.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Fipronil-S-Methoprene pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.