Cat · Felis catus · typical adult weight 2.50–7.00 kg
Emodepside is dosed at 3 mg/kg TOPICAL Single application in cats, per Profender - 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4h-pyrazino(2,1-a)isoquinolin-4-one, emodepside solution for cats [US product label]. In: Elanco; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=31f0a4ec-2a29-4de5-971b-633e109b276d — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.471 (2026-08-01).. Emodepside is used in cats for Roundworms, hookworms, tapeworms. Routes documented in cats: TOPICAL. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Emodepside in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Profender
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL | 3 mg/kg | Single application | Single topical application per treatment | Roundworms, hookworms, tapeworms | Strong | Profender - 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4h-pyrazino(2,1-a)isoquinolin-4-one, emodepside solution for cats [US product label]. In: Elanco; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=31f0a4ec-2a29-4de5-971b-633e109b276d — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.471 (2026-08-01). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Stimulates presynaptic secretin receptors (SLO-1 potassium channels) in nematodes, causing paralysis. Novel mechanism unrelated to other anthelmintics.
Topical formulation for cats. Do not allow oral ingestion of topical product (salivation, vomiting). Novel anthelmintic class with activity against some resistant nematodes.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Emodepside dose range in cats, with cited source references: TOPICAL 3 mg/kg Single application. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Emodepside in cats: TOPICAL.
Cited course lengths for Emodepside in cats include: Single topical application per treatment. Duration depends on the indication — match it to the specific dose rule in the table above.
Emodepside is indicated in cats for: Roundworms, hookworms, tapeworms.
These are general warnings for Emodepside across species; consult the cat dosing table above for species-specific guidance. Topical formulation for cats. Do not allow oral ingestion of topical product (salivation, vomiting). Novel anthelmintic class with activity against some resistant nematodes.
Why a species-specific page? Emodepside pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.