Cat · Felis catus · typical adult weight 2.50–7.00 kg
Emodepside Topical is dosed at 3 mg/kg Topical once in cats, per Profender - 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4h-pyrazino(2,1-a)isoquinolin-4-one, emodepside solution for cats [US product label]. In: Elanco; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=31f0a4ec-2a29-4de5-971b-633e109b276d — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.471 (2026-08-01). — Plumb's 10th ed (held) printed p.444, Emodepside/Praziquantel monograph spanning p.442-444; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Emodepside Topical is used in cats for Roundworms, hookworms, tapeworms. Routes documented in cats: Topical. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Emodepside Topical in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Profender
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Topical | 3 mg/kg | once | Single application | Roundworms, hookworms, tapeworms | Strong | Profender - 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4h-pyrazino(2,1-a)isoquinolin-4-one, emodepside solution for cats [US product label]. In: Elanco; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=31f0a4ec-2a29-4de5-971b-633e109b276d — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.471 (2026-08-01). — Plumb's 10th ed (held) printed p.444, Emodepside/Praziquantel monograph spanning p.442-444; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (ml/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.14 | TOPICAL | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.160 | minimum dose 0.14 ml/kg applied topically once per treatment cycle. For the lungworm Aelurostrongylus abstr |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Depsipeptide activating presynaptic latrophilin receptors and SLO-1 potassium channels causing paralysis and death of nematodes and cestodes.
Combined with praziquantel in Profender (cats). Topical application. Do not allow oral ingestion. Salivation if cat licks application site. Effective against roundworms, hookworms, tapeworms.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Emodepside Topical dose range in cats, with cited source references: Topical 3 mg/kg once. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Emodepside Topical in cats: Topical.
Cited course lengths for Emodepside Topical in cats include: Single application. Duration depends on the indication — match it to the specific dose rule in the table above.
Emodepside Topical is indicated in cats for: Roundworms, hookworms, tapeworms.
These are general warnings for Emodepside Topical across species; consult the cat dosing table above for species-specific guidance. Combined with praziquantel in Profender (cats). Topical application. Do not allow oral ingestion. Salivation if cat licks application site. Effective against roundworms, hookworms, tapeworms.
Why a species-specific page? Emodepside Topical pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.