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Atovaquone

Mepron

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antiparasitic

Routes

PO

Indications

Babesiosis (with azithromycin)Cytauxzoonosis

Mechanism of Action

Inhibits mitochondrial electron transport at cytochrome bc1 complex (Complex III) in protozoa. Active against Pneumocystis, Toxoplasma, Babesia.

Side effects & warnings

Must be taken with fatty food for absorption. GI upset common. Often combined with azithromycin for Babesia. Limited veterinary data.

Species with Atovaquone dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Moderate×1Weak×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO13.3 mg/kgq8hModeratePlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)PO15 mg/kgq8hWeakPlumb's Veterinary Drug Handbook, 9th Ed

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