Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Benznidazole is dosed at 5–7 mg/kg PO q24h or q12h for 2 months in dogs, per Riviere JE, Papich MG (eds). Veterinary Pharmacology and Therapeutics, 10th Ed, Ch.42 Antiprotozoan Drugs, p.1159 (Clinical Use — Dogs), corroborated by the summary table on p.1153; the page attributes the canine regimen to Barr (2006) and Santos et al. (2012), both in-species dog work on Trypanosoma cruzi.. Benznidazole is used in dogs for Chagas disease (T. cruzi). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Benznidazole in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rochagan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 5–7 mg/kg | q24h or q12h for 2 months | 60-90 days | Chagas disease (T. cruzi) | Moderate | Riviere JE, Papich MG (eds). Veterinary Pharmacology and Therapeutics, 10th Ed, Ch.42 Antiprotozoan Drugs, p.1159 (Clinical Use — Dogs), corroborated by the summary table on p.1153; the page attributes the canine regimen to Barr (2006) and Santos et al. (2012), both in-species dog work on Trypanosoma cruzi. |
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Nitroimidazole derivative generating free radicals that damage Trypanosoma cruzi DNA and proteins. Trypanocidal.
Used for Chagas disease (T. cruzi) in dogs. GI upset, anorexia, neutropenia possible. More effective in acute phase. Prolonged treatment (60-90 days).
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Benznidazole dose range in dogs, with cited source references: PO 5–7 mg/kg q24h or q12h for 2 months. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Benznidazole in dogs: PO.
Cited course lengths for Benznidazole in dogs include: 60-90 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Benznidazole is indicated in dogs for: Chagas disease (T. cruzi).
These are general warnings for Benznidazole across species; consult the dog dosing table above for species-specific guidance. Used for Chagas disease (T. cruzi) in dogs. GI upset, anorexia, neutropenia possible. More effective in acute phase. Prolonged treatment (60-90 days).
Why a species-specific page? Benznidazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.