Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Emodepside Oral is dosed at 0.45 mg/kg PO Single dose in dogs, per Altreuther G, Gasda N, Adler K et al. (2011) Field evaluations of the efficacy and safety of Emodepside plus toltrazuril (Procox oral suspension for dogs) against naturally acquired nematode and Isospora spp. infections in dogs. Parasitology Research 109(S1), 21-28 doi:10.1007/s00436-011-2399-z — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.160 (2026-08-01).. Emodepside Oral is used in dogs for Nematode infections (multi-drug resistant). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Emodepside Oral in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Profender Oral
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.45 mg/kg | Single dose | Single treatment; repeat as needed | Nematode infections (multi-drug resistant) | Moderate | Altreuther G, Gasda N, Adler K et al. (2011) Field evaluations of the efficacy and safety of Emodepside plus toltrazuril (Procox oral suspension for dogs) against naturally acquired nematode and Isospora spp. infections in dogs. Parasitology Research 109(S1), 21-28 doi:10.1007/s00436-011-2399-z — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.160 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Acts on latrophilin receptors (SLO-1 K+ channels) in nematode neuromuscular junction, causing flaccid paralysis. Novel mechanism without cross-resistance to other anthelmintics.
Generally well tolerated. Effective against larval stages. Some strains of ivermectin-resistant parasites remain susceptible. P-glycoprotein substrate.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Emodepside Oral dose range in dogs, with cited source references: PO 0.45 mg/kg Single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Emodepside Oral in dogs: PO.
Cited course lengths for Emodepside Oral in dogs include: Single treatment; repeat as needed. Duration depends on the indication — match it to the specific dose rule in the table above.
Emodepside Oral is indicated in dogs for: Nematode infections (multi-drug resistant).
These are general warnings for Emodepside Oral across species; consult the dog dosing table above for species-specific guidance. Generally well tolerated. Effective against larval stages. Some strains of ivermectin-resistant parasites remain susceptible. P-glycoprotein substrate.
Why a species-specific page? Emodepside Oral pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.