Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Emodepside Oral is used in dog for Nematode infections (multi-drug resistant). Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Emodepside Oral in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Profender Oral
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.45 mg/kg | Single dose | Single treatment; repeat as needed | Nematode infections (multi-drug resistant) | Moderate | BSAVA Small Animal Formulary, 10th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Acts on latrophilin receptors (SLO-1 K+ channels) in nematode neuromuscular junction, causing flaccid paralysis. Novel mechanism without cross-resistance to other anthelmintics.
Generally well tolerated. Effective against larval stages. Some strains of ivermectin-resistant parasites remain susceptible. P-glycoprotein substrate.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Emodepside Oral pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.