Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Doramectin is dosed at 0.2–0.6 mg/kg SC q7-14d in dogs, per Murayama N, Shibata K, Nagata M. Efficacy of weekly oral doramectin treatment in canine demodicosis. Vet Rec. 2010;167:63-64. doi:10.1136/vr.b4885; Upadhyay A, Srivastava M, Srivastava A, et al. Therapeutic potential of doramectin against canine sarcoptic mange. Journal of Entomology and Zoology Studies. 2019;7(4):403-407. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.452 (2026-08-01). — Plumb's 10th ed (held) printed p.424, Doramectin monograph spanning p.424-425; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 16 — "0.2 mg/kg weekly16 SC was given to alpacas, peak concentr" — which resolves in the monograph's own reference list to: Upadhyay A, Srivastava M, Srivastava A, et al. Therapeutic potential of doramectin against canine sarcoptic mange. Journal of Entomology and Zoology Studies. 2019;7(4):403-407. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose.. Doramectin is used in dogs for Demodectic mange, sarcoptic mange. Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Doramectin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Dectomax
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 0.2–0.6 mg/kg | q7-14d | Until 2 negative skin scrapings | Demodectic mange, sarcoptic mange | Moderate | Murayama N, Shibata K, Nagata M. Efficacy of weekly oral doramectin treatment in canine demodicosis. Vet Rec. 2010;167:63-64. doi:10.1136/vr.b4885; Upadhyay A, Srivastava M, Srivastava A, et al. Therapeutic potential of doramectin against canine sarcoptic mange. Journal of Entomology and Zoology Studies. 2019;7(4):403-407. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.452 (2026-08-01). — Plumb's 10th ed (held) printed p.424, Doramectin monograph spanning p.424-425; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 16 — "0.2 mg/kg weekly16 SC was given to alpacas, peak concentr" — which resolves in the monograph's own reference list to: Upadhyay A, Srivastava M, Srivastava A, et al. Therapeutic potential of doramectin against canine sarcoptic mange. Journal of Entomology and Zoology Studies. 2019;7(4):403-407. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mcg/kg) | Route | Source | As printed |
|---|---|---|---|
| 600 | SC | Papich Saunders Handbook of Veterinary Drugs, 4th edp.295 | • Demodex treatment: 600 mcg/kg/wk for 5-23 weeks SQ. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds glutamate-gated chloride channels in invertebrate nerve/muscle cells, causing paralysis and death of parasites.
MDR1-sensitive breeds: CONTRAINDICATED (Collies, etc.). Long duration of action (single injection). Not for use in cats. Approved for cattle/swine — extra-label in small animals.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Doramectin dose range in dogs, with cited source references: SC 0.2–0.6 mg/kg q7-14d. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Doramectin in dogs: SC.
Cited course lengths for Doramectin in dogs include: Until 2 negative skin scrapings. Duration depends on the indication — match it to the specific dose rule in the table above.
Doramectin is indicated in dogs for: Demodectic mange, sarcoptic mange.
These are general warnings for Doramectin across species; consult the dog dosing table above for species-specific guidance. MDR1-sensitive breeds: CONTRAINDICATED (Collies, etc.). Long duration of action (single injection). Not for use in cats. Approved for cattle/swine — extra-label in small animals.
Why a species-specific page? Doramectin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.