Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Doramectin is dosed at 0.2–0.6 mg/kg SC q7-14d in dogs, per Murayama N, Shibata K, Nagata M. Efficacy of weekly oral doramectin treatment in canine demodicosis. Vet Rec. 2010;167:63-64. doi:10.1136/vr.b4885; Upadhyay A, Srivastava M, Srivastava A, et al. Therapeutic potential of doramectin against canine sarcoptic mange. Journal of Entomology and Zoology Studies. 2019;7(4):403-407. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.452 (2026-08-01).. Doramectin is used in dogs for Demodectic mange, sarcoptic mange. Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Doramectin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Dectomax
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 0.2–0.6 mg/kg | q7-14d | Until 2 negative skin scrapings | Demodectic mange, sarcoptic mange | Moderate | Murayama N, Shibata K, Nagata M. Efficacy of weekly oral doramectin treatment in canine demodicosis. Vet Rec. 2010;167:63-64. doi:10.1136/vr.b4885; Upadhyay A, Srivastava M, Srivastava A, et al. Therapeutic potential of doramectin against canine sarcoptic mange. Journal of Entomology and Zoology Studies. 2019;7(4):403-407. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.452 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds glutamate-gated chloride channels in invertebrate nerve/muscle cells, causing paralysis and death of parasites.
MDR1-sensitive breeds: CONTRAINDICATED (Collies, etc.). Long duration of action (single injection). Not for use in cats. Approved for cattle/swine — extra-label in small animals.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Doramectin dose range in dogs, with cited source references: SC 0.2–0.6 mg/kg q7-14d. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Doramectin in dogs: SC.
Cited course lengths for Doramectin in dogs include: Until 2 negative skin scrapings. Duration depends on the indication — match it to the specific dose rule in the table above.
Doramectin is indicated in dogs for: Demodectic mange, sarcoptic mange.
These are general warnings for Doramectin across species; consult the dog dosing table above for species-specific guidance. MDR1-sensitive breeds: CONTRAINDICATED (Collies, etc.). Long duration of action (single injection). Not for use in cats. Approved for cattle/swine — extra-label in small animals.
Why a species-specific page? Doramectin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.