ExoticRx · exoticrx.com/drugs/doramectin
US brand names:Dectomax
Doramectin is dosed at 0.2–0.4 mg/kg SC q14d in bearded dragons, per Carpenter's Exotic Animal Formulary, 6th Ed. Verify against current literature before clinical use.
Binds glutamate-gated chloride channels in invertebrate nerve/muscle cells, causing paralysis and death of parasites.
MDR1-sensitive breeds: CONTRAINDICATED (Collies, etc.). Long duration of action (single injection). Not for use in cats. Approved for cattle/swine — extra-label in small animals.
Species references:All Bearded Dragon drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 0.2–0.6 mg/kg | q7-14d | Moderate | Murayama N, Shibata K, Nagata M. Efficacy of weekly oral doramectin treatment in canine demodicosis. Vet Rec. 2010;167:63-64. doi:10.1136/vr.b4885; Upadhyay A, Srivastava M, Srivastava A, et al. Therapeutic potential of doramectin against canine sarcoptic mange. Journal of Entomology and Zoology Studies. 2019;7(4):403-407. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.452 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.