Amphibian · Xenopus laevis · typical adult weight 0.05–0.25 kg
Piperazine is dosed at 50 mg/kg p.o. repeat in 14 days in african clawed frogs, per Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.255. — LOCATOR CONVENTION 2026-08-07: the bare 'p.255' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.241; verified by finding the drug named there. If you are holding the book, turn to p.241. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712. Piperazine (Antiparasitic) has cited veterinary dosing for african clawed frogs. Routes documented in african clawed frogs: p.o.. A typical adult african clawed frog weighs 0.05–0.25 kg. ExoticRx lists 1 cited dose rule for Piperazine in african clawed frogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Pipa-Tabs, Sergeants Worm Away
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| p.o. | 50 mg/kg | repeat in 14 days | — | Moderate | Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.255. — LOCATOR CONVENTION 2026-08-07: the bare 'p.255' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.241; verified by finding the drug named there. If you are holding the book, turn to p.241. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 50 | PO | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.255 | 50 mg/kg p.o., repeat in 14 days |
| 50 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 3.3 | 50 mg/kg PO, repeat in 2 wk |
| 40–60 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 40-60 mg/kg PO, repeat in 14 days174 Most species/strongyles, ascarids; poor efficacy at < 400 mg/kg174 |
| 100–200 |
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These ranges are per kg. Enter your african clawed frog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
GABA agonist that causes flaccid paralysis in ascarids (roundworms). Worms are expelled alive by peristalsis.
Only effective against ascarids (roundworms). Wide safety margin. May cause vomiting at high doses. Do not combine with pyrantel (antagonistic).
Species-specific contraindications and adverse-reaction reports for african clawed frogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Piperazine dose range in african clawed frogs, with cited source references: p.o. 50 mg/kg repeat in 14 days. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Piperazine in african clawed frogs: p.o..
These are general warnings for Piperazine across species; consult the african clawed frog dosing table above for species-specific guidance. Only effective against ascarids (roundworms). Wide safety margin. May cause vomiting at high doses. Do not combine with pyrantel (antagonistic).
Why a species-specific page? Piperazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in african clawed frogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| — |
| Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 |
| 100-200 mg/kg PO135 Crocodilians |
| 50 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.3 | 50 mg/kg PO, repeat in 2 wk52 Gastrointestinal nematodes |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.