Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Amphotericin B is dosed at 1 mg/kg IV q24h in rabbits, per Plumb DC. Plumb's Veterinary Drug Handbook, 9th ed., Wiley Blackwell, Ames, IA; 2018. | Sanati H, Ramos C, Bayer A, et al. Combination therapy with amphotericin B and fluconazole against invasive candidiasis in neutropenic-mouse and infective-endocarditis rabbit models. Antimicrob Agents Chemother. 1997;41:1345-1348. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.846 (2026-08-01, PENDING REVIEW). Amphotericin B is used in rabbits for Invasive aspergillosis / severe fungal infection. Routes documented in rabbits: IV. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Amphotericin B in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Fungizone, Abelcet
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IV | 1 mg/kg | q24h | Invasive aspergillosis / severe fungal infection | Weak | Plumb DC. Plumb's Veterinary Drug Handbook, 9th ed., Wiley Blackwell, Ames, IA; 2018. | Sanati H, Ramos C, Bayer A, et al. Combination therapy with amphotericin B and fluconazole against invasive candidiasis in neutropenic-mouse and infective-endocarditis rabbit models. Antimicrob Agents Chemother. 1997;41:1345-1348. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.846 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your rabbit's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds ergosterol in fungal cell membranes, creating pores that cause leakage of intracellular contents and cell death.
Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amphotericin B dose range in rabbits, with cited source references: IV 1 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amphotericin B in rabbits: IV.
Amphotericin B is indicated in rabbits for: Invasive aspergillosis / severe fungal infection.
These are general warnings for Amphotericin B across species; consult the rabbit dosing table above for species-specific guidance. Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Why a species-specific page? Amphotericin B pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.