ExoticRx · exoticrx.com/drugs/amphotericin-b
Amphotericin B
Fungizone, Abelcet
Drug Class
Routes
Indications
Mechanism of Action
Binds ergosterol in fungal cell membranes, creating pores that cause leakage of intracellular contents and cell death.
Side effects & warnings
Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Species with Amphotericin B dosing data (2 dose rules)
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Evidence levels across 2 dose rules
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by a published source
- · Plumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (2 of 2 cited rules)
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
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View PlansArticles mentioning Amphotericin B
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- Antibiotic Selection in Exotic Animals: Principles and PitfallsHow to choose an antibiotic for rabbits, guinea pigs, parrots, and reptiles — with the species-specific contraindications general practice reaches for first by reflex.
- African Grey Parrot Drug Dosing: A Vet ReferenceAntibiotic, antifungal, and supportive-care dosing for Psittacus erithacus — and the avian-specific physiology that should change your prescribing.
More Antifungal drugs
Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.