ExoticRx · exoticrx.com/drugs/amphotericin-b
US brand names:Fungizone, Abelcet
Amphotericin B is dosed at 0.5 mg/kg IV q48-72h in ball pythons, per Carpenter JW, Klaphake E, Gibbons PM, et al. Reptile formulary. In: Divers SJ, Stahl SJ, eds. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019:1191-1211. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.221 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.3 (Antifungal Agents Used in Reptiles). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530. Verify against current literature before clinical use.
Binds ergosterol in fungal cell membranes, creating pores that cause leakage of intracellular contents and cell death.
Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
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A dog/cat sample is shown here. Cited dosing for all 14 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.5 mg/kg | q48h (every other day); practically 3x/week | Weak | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Amphotericin B, Dosages, DOGS, printed p. 76 (corpus PDF p. 103) — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Cat (Domestic) | IV | 0.25 mg/kg | q48h (every other day); practically 3x/week | Weak | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Amphotericin B, Dosages, CATS, printed p. 76 (corpus PDF p. 103) — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.