ExoticRx · exoticrx.com/drugs/amphotericin-b-liposomal
US brand names:AmBisome
Amphotericin B Liposomal is dosed at 1–4 mg/kg Nebulization 15-60 min per treatment; repeat q4-12h in african grey parrots, per Carpenter's Exotic Animal Formulary, 6th Ed — Carpenter's Exotic Animal Formulary, 6th ed, Table 5.8 (corpus PDF pp.465-467); located 2026-08-06 by chapter-governed table: this table is in the chapter covering this species and names this drug. NOTE: the served figure was matched against the table as a whole, not against this drug's own row, so confirm the number on the page before relying on it. The held copy has no printed page numbers, so the numbered table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Verify against current literature before clinical use.
Liposomal encapsulation targets drug to fungal cells while reducing exposure to mammalian cell membranes. Binds ergosterol causing membrane disruption.
Least nephrotoxic amphotericin B formulation. Still monitor renal function. Infusion reactions less common. Preferred formulation in veterinary practice.
Species references:All African Grey Parrot drugsAll Cat (Domestic) drugsAll Dog (Domestic) drugsAll Duck drugs
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A dog/cat sample is shown here. Cited dosing for all 4 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 1–5 mg/kg | q48h or 3x/week | Strong | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.74, Amphotericin B monograph spanning p.74-77; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Cat (Domestic) | IV | 1–3 mg/kg | q48h or 3x/week | Moderate | Foy DS, Trepanier LA. Antifungal Treatment of Small Animal Veterinary Patients. Veterinary Clinics of North America-Small Animal Practice. 2010;40(6):1171-1188. doi:10.1016/j.cvsm.2010.07.006 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.103 (2026-08-01). — Plumb's 10th ed (held) printed p.74, Amphotericin B monograph spanning p.74-77; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, |
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