Amphotericin B Liposomal for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Amphotericin B Liposomal is used in dog for Invasive fungal infections. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Amphotericin B Liposomal in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: AmBisome
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 1–5 mg/kg | q48h or 3x/week | Cumulative dose 24-30 mg/kg total | Invasive fungal infections | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Liposomal encapsulation targets drug to fungal cells while reducing exposure to mammalian cell membranes. Binds ergosterol causing membrane disruption.
Side effects & warnings
Least nephrotoxic amphotericin B formulation. Still monitor renal function. Infusion reactions less common. Preferred formulation in veterinary practice.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antifungal drugs with dog dosing
Amphotericin B Liposomal dosing in other species
Why a species-specific page? Amphotericin B Liposomal pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.