Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Amphotericin B Lipid Complex is dosed at 1–3 mg/kg IV q48h or 3x/week in dogs, per Krawiec DR, McKiernan BC, Twardock AR, et al. Use of an amphotericin B lipid complex for treatment of blastomycosis in dogs. J Am Vet Med Assoc. 1996;209(12):2073-2075. doi:10.2460/javma.1996.209.12.2073 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.103 (2026-08-01).. Amphotericin B Lipid Complex is used in dogs for Systemic fungal infections (blastomycosis, histoplasmosis, aspergillosis). Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Amphotericin B Lipid Complex in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Abelcet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 1–3 mg/kg | q48h or 3x/week | Cumulative dose 12-27 mg/kg total | Systemic fungal infections (blastomycosis, histoplasmosis, aspergillosis) | Moderate | Krawiec DR, McKiernan BC, Twardock AR, et al. Use of an amphotericin B lipid complex for treatment of blastomycosis in dogs. J Am Vet Med Assoc. 1996;209(12):2073-2075. doi:10.2460/javma.1996.209.12.2073 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.103 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds ergosterol creating membrane pores. Lipid complex formulation reduces nephrotoxicity by preferentially distributing to RES tissues.
Less nephrotoxic than conventional amphotericin B but still significant. Infusion reactions. Monitor renal function and electrolytes.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amphotericin B Lipid Complex dose range in dogs, with cited source references: IV 1–3 mg/kg q48h or 3x/week. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amphotericin B Lipid Complex in dogs: IV.
Cited course lengths for Amphotericin B Lipid Complex in dogs include: Cumulative dose 12-27 mg/kg total. Duration depends on the indication — match it to the specific dose rule in the table above.
Amphotericin B Lipid Complex is indicated in dogs for: Systemic fungal infections (blastomycosis, histoplasmosis, aspergillosis).
These are general warnings for Amphotericin B Lipid Complex across species; consult the dog dosing table above for species-specific guidance. Less nephrotoxic than conventional amphotericin B but still significant. Infusion reactions. Monitor renal function and electrolytes.
Why a species-specific page? Amphotericin B Lipid Complex pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.