Amphotericin B for Russian Tortoises
Reptile · Testudo horsfieldii · typical adult weight 0.23–0.91 kg
Amphotericin B is dosed at 0.1 mg/kg intrapulmonary q 24 h for 28 d in russian tortoises, per Merck Veterinary Manual. Antimicrobial Drugs Used in Reptiles (dosing table). Rahway (NJ): Merck & Co.; accessed 2026. URL: https://www.merckvetmanual.com/multimedia/table/antimicrobial-drugs-used-in-reptiles. Amphotericin B is used in russian tortoises for Aspergillosis. Routes documented in russian tortoises: intrapulmonary. A typical adult russian tortoise weighs 0.23–0.91 kg. ExoticRx lists 1 cited dose rule for Amphotericin B in russian tortoises, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Fungizone, Abelcet
Dose ranges
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| intrapulmonary | 0.1 mg/kg | q 24 h for 28 d | Aspergillosis | Weak | Merck Veterinary Manual. Antimicrobial Drugs Used in Reptiles (dosing table). Rahway (NJ): Merck & Co.; accessed 2026. URL: https://www.merckvetmanual.com/multimedia/table/antimicrobial-drugs-used-in-reptiles |
Need the exact dose for your patient?
These ranges are per kg. Enter your russian tortoise's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Binds ergosterol in fungal cell membranes, creating pores that cause leakage of intracellular contents and cell death.
Side effects & warnings
Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Species-specific contraindications and adverse-reaction reports for russian tortoises may differ from canine / feline reference data — consult the primary citations listed with each rule.
Frequently asked questions
What is the dose of Amphotericin B for Russian Tortoises?
Amphotericin B dose range in russian tortoises, with cited source references: intrapulmonary 0.1 mg/kg q 24 h for 28 d.
How is Amphotericin B administered in Russian Tortoises?
Documented routes for Amphotericin B in russian tortoises: intrapulmonary.
What conditions does Amphotericin B treat in Russian Tortoises?
Amphotericin B is indicated in russian tortoises for: Aspergillosis.
What are the side effects of Amphotericin B in Russian Tortoises?
These are general warnings for Amphotericin B across species; consult the russian tortoise dosing table above for species-specific guidance. Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Other Antifungal drugs with russian tortoise dosing
Amphotericin B dosing in other species
Why a species-specific page? Amphotericin B pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in russian tortoises — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.