Reptile · Tiliqua scincoides · typical adult weight 0.25–0.60 kg
Amphotericin B is dosed at 0.5 mg/kg IV q48-72h in blue-tongue skinks, per Carpenter JW, Klaphake E, Gibbons PM, et al. Reptile formulary. In: Divers SJ, Stahl SJ, eds. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019:1191-1211. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.221 — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.3 (Antifungal Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location.. Amphotericin B is used in blue-tongue skinks for Systemic mycosis. Routes documented in blue-tongue skinks: IV. A typical adult blue-tongue skink weighs 0.25–0.60 kg. ExoticRx lists 1 cited dose rule for Amphotericin B in blue-tongue skinks, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Fungizone, Abelcet
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IV | 0.5 mg/kg | q48-72h |
| Systemic mycosis |
| Weak |
| Carpenter JW, Klaphake E, Gibbons PM, et al. Reptile formulary. In: Divers SJ, Stahl SJ, eds. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019:1191-1211. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.221 — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.3 (Antifungal Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.5–1 | IV | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.35 | 0.5-1 mg/kg i.v., intracoelomic q24-72h for 2-4 weeks, concurrent fluid therapy is advised due to po |
| 0.5 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 0.5 mg/kg IV q48-72h89 0.5-1 mg/kg IV, ICe q24-72h × 1 mg/kg IT q24h × 14-28 days14 0.1 mg/kg intrapulmonary q24h Most species/nephrotoxic; can use in combination with ketoconazole |
| 0.5–1 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 0.5 mg/kg IV q48-72h89 0.5-1 mg/kg IV, ICe q24-72h × 1 mg/kg IT q24h × 14-28 days14 0.1 mg/kg intrapulmonary q24h Most species/nephrotoxic; can use in combination with ketoconazole |
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These ranges are per kg. Enter your blue-tongue skink's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds ergosterol in fungal cell membranes, creating pores that cause leakage of intracellular contents and cell death.
Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Species-specific contraindications and adverse-reaction reports for blue-tongue skinks may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amphotericin B dose range in blue-tongue skinks, with cited source references: IV 0.5 mg/kg q48-72h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amphotericin B in blue-tongue skinks: IV.
Amphotericin B is indicated in blue-tongue skinks for: Systemic mycosis.
These are general warnings for Amphotericin B across species; consult the blue-tongue skink dosing table above for species-specific guidance. Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Why a species-specific page? Amphotericin B pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in blue-tongue skinks — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 1 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 0.5 mg/kg IV q48-72h89 0.5-1 mg/kg IV, ICe q24-72h × 1 mg/kg IT q24h × 14-28 days14 0.1 mg/kg intrapulmonary q24h Most species/nephrotoxic; can use in combination with ketoconazole |
| 0.1 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 0.5 mg/kg IV q48-72h89 0.5-1 mg/kg IV, ICe q24-72h × 1 mg/kg IT q24h × 14-28 days14 0.1 mg/kg intrapulmonary q24h Most species/nephrotoxic; can use in combination with ketoconazole |
| 1 | ICE | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 1 mg/kg q24h ICe × 2-4 wk185 5 mg/150 mL saline × 1 hr nebu × 7 days143 Crocodilians lization q12h Most species/pneumonia |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.