Cat · Felis catus · typical adult weight 2.50–7.00 kg
Amphotericin B is dosed at 0.25 mg/kg IV q48h (every other day); practically 3x/week in cats, per Plumb's Veterinary Drug Handbook, 9th Ed — Amphotericin B, Dosages, CATS, printed p. 76 (corpus PDF p. 103). Amphotericin B is used in cats for Systemic mycoses (cryptococcosis). Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Amphotericin B in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Fungizone, Abelcet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.25 mg/kg | q48h (every other day); practically 3x/week | Variable — monitor cumulative dose | Systemic mycoses (cryptococcosis) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed — Amphotericin B, Dosages, CATS, printed p. 76 (corpus PDF p. 103) |
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Binds ergosterol in fungal cell membranes, creating pores that cause leakage of intracellular contents and cell death.
Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amphotericin B dose range in cats, with cited source references: IV 0.25 mg/kg q48h (every other day); practically 3x/week. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amphotericin B in cats: IV.
Cited course lengths for Amphotericin B in cats include: Variable — monitor cumulative dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Amphotericin B is indicated in cats for: Systemic mycoses (cryptococcosis).
These are general warnings for Amphotericin B across species; consult the cat dosing table above for species-specific guidance. Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Why a species-specific page? Amphotericin B pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.