Cat · Felis catus · typical adult weight 2.50–7.00 kg
Amphotericin B is dosed at 0.25 mg/kg IV q48h (every other day); practically 3x/week in cats, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Amphotericin B, Dosages, CATS, printed p. 76 (corpus PDF p. 103) — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Amphotericin B is used in cats for Systemic mycoses (cryptococcosis). Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Amphotericin B in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Fungizone, Abelcet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.25 mg/kg | q48h (every other day); practically 3x/week | Variable — monitor cumulative dose | Systemic mycoses (cryptococcosis) | Weak |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.5–0.8 | — | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.43 | subcutaneous alternative): Conventional amphotericin: 0.5-0.8 mg/kg added to 400-50 |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
Need the exact dose for your patient?
These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds ergosterol in fungal cell membranes, creating pores that cause leakage of intracellular contents and cell death.
Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amphotericin B dose range in cats, with cited source references: IV 0.25 mg/kg q48h (every other day); practically 3x/week. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amphotericin B in cats: IV.
Cited course lengths for Amphotericin B in cats include: Variable — monitor cumulative dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Amphotericin B is indicated in cats for: Systemic mycoses (cryptococcosis).
These are general warnings for Amphotericin B across species; consult the cat dosing table above for species-specific guidance. Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Why a species-specific page? Amphotericin B pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.