Cat · Felis catus · typical adult weight 2.50–7.00 kg
Fluconazole is used in cat for Severe systemic mycoses, Cryptococcosis, dermatophytosis, Nasal cryptococcosis, CNS cryptococcosis. Routes documented in cat: IV, PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 4 cited dose rules for Fluconazole in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Diflucan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 5–10 mg/kg | q12-24h | Until oral feasible | Severe systemic mycoses | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 5–10 mg/kg | q12-24h | Weeks to months | Cryptococcosis, dermatophytosis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 5–10 mg/kg | q12h | Until antigen titers negative | Nasal cryptococcosis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 10–15 mg/kg | q12h | 6+ months; until antigen negative | CNS cryptococcosis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits fungal cytochrome P450 enzyme 14-alpha-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane.
Hepatotoxic: monitor liver enzymes during prolonged therapy. Drug interactions via CYP450 inhibition. Good CNS and ocular penetration.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Fluconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.