Cat · Felis catus · typical adult weight 2.50–7.00 kg
Flucytosine is dosed at 25–50 mg/kg PO q6-8h in cats, per Pressler BM. Chapter 63: Candidiasis and Rhodotorulosis. In: Greene CE, ed. Infectious Diseases of the Dog and Cat. 4th ed. Elsevier; 2011:666-671. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.562 (2026-08-01).. Flucytosine is used in cats for Cryptococcosis (with amphotericin B). Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Flucytosine in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Ancobon
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 25–50 mg/kg | q6-8h | Weeks to months | Cryptococcosis (with amphotericin B) | Moderate | Pressler BM. Chapter 63: Candidiasis and Rhodotorulosis. In: Greene CE, ed. Infectious Diseases of the Dog and Cat. 4th ed. Elsevier; 2011:666-671. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.562 (2026-08-01). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Converted to 5-fluorouracil inside fungal cells, inhibiting DNA and RNA synthesis. Synergistic with amphotericin B.
Rapid resistance if used alone — always combine with amphotericin B or azole. Bone marrow suppression, GI toxicity. Monitor CBC. Teratogenic.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Flucytosine dose range in cats, with cited source references: PO 25–50 mg/kg q6-8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Flucytosine in cats: PO.
Cited course lengths for Flucytosine in cats include: Weeks to months. Duration depends on the indication — match it to the specific dose rule in the table above.
Flucytosine is indicated in cats for: Cryptococcosis (with amphotericin B).
These are general warnings for Flucytosine across species; consult the cat dosing table above for species-specific guidance. Rapid resistance if used alone — always combine with amphotericin B or azole. Bone marrow suppression, GI toxicity. Monitor CBC. Teratogenic.
Why a species-specific page? Flucytosine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.