Cat · Felis catus · typical adult weight 2.50–7.00 kg
Itraconazole is dosed at 5 mg/kg PO q24h in cats, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.734 (2026-08-01). — Plumb's 10th ed (held) printed p.704, Itraconazole monograph spanning p.704-708; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Itraconazole is used in cats for Ringworm (pulse therapy), Dermatophytosis, cryptococcosis, sporotrichosis, Aspergillosis (sinonasal). Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 3 cited dose rules for Itraconazole in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Sporanox, Itrafungol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 5 mg/kg | q24h | 1 week on, 1 week off; 3-4 cycles | Ringworm (pulse therapy) | Strong |
| Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.734 (2026-08-01). — Plumb's 10th ed (held) printed p.704, Itraconazole monograph spanning p.704-708; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| PO | 5–10 mg/kg | q24h | Weeks to months | Dermatophytosis, cryptococcosis, sporotrichosis | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.734 (2026-08-01). — Plumb's 10th ed (held) printed p.704, Itraconazole monograph spanning p.704-708; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| PO | 5–10 mg/kg | q24h (or the same daily total divided q12h) | Months | Aspergillosis (sinonasal) | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.704, Itraconazole monograph spanning p.704-708; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.705, Itraconazole monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 5 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.231 | 5 mg/kg p.o. q24h. 4-20 weeks of treatment may be needed, dependent upon culture results. Pulse d |
| 5 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.447 | • 5 mg/kg PO once daily. Alternatively, 50 mg (total dose) once per day; or 100 mg |
| 1.5–3 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.447 | • Dermatophytes: 1.5-3 mg/kg (up to 5 mg/kg) q24h PO for 15 days (although |
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Inhibits fungal 14-alpha-demethylase, blocking ergosterol synthesis. Lipophilic with high tissue concentrations.
Hepatotoxic: monitor liver enzymes. Requires acid pH for capsule absorption (give with food). Negative inotropic effect — avoid in animals with heart failure. CYP3A4 inhibitor.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Itraconazole dose ranges in cats, with cited source references: PO 5 mg/kg q24h; PO 5–10 mg/kg q24h; PO 5–10 mg/kg q24h (or the same daily total divided q12h). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Itraconazole in cats: PO.
Cited course lengths for Itraconazole in cats include: 1 week on, 1 week off; 3-4 cycles; Weeks to months; Months. Duration depends on the indication — match it to the specific dose rule in the table above.
Itraconazole is indicated in cats for: Ringworm (pulse therapy), Dermatophytosis, cryptococcosis, sporotrichosis, Aspergillosis (sinonasal).
These are general warnings for Itraconazole across species; consult the cat dosing table above for species-specific guidance. Hepatotoxic: monitor liver enzymes. Requires acid pH for capsule absorption (give with food). Negative inotropic effect — avoid in animals with heart failure. CYP3A4 inhibitor.
Why a species-specific page? Itraconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 5–10 |
| PO |
| Papich Saunders Handbook of Veterinary Drugs, 4th edp.447 |
| • 5-10 mg/kg q24h PO for 7 days, then alternating with 1 week on and 1 week off. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.