Cat · Felis catus · typical adult weight 2.50–7.00 kg
Itraconazole is dosed at 5–10 mg/kg PO q12-24h in cats, per Plumb's Veterinary Drug Handbook, 9th Ed. Itraconazole is used in cats for Aspergillosis (sinonasal), Dermatophytosis, cryptococcosis, sporotrichosis, Ringworm (pulse therapy). Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 3 cited dose rules for Itraconazole in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Sporanox, Itrafungol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 5–10 mg/kg | q12-24h | Months | Aspergillosis (sinonasal) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 5–10 mg/kg | q24h | Weeks to months | Dermatophytosis, cryptococcosis, sporotrichosis | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.734 (2026-08-01). |
| PO | 5–10 mg/kg | q24h | 1 week on, 1 week off; 3-4 cycles | Ringworm (pulse therapy) | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.734 (2026-08-01). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits fungal 14-alpha-demethylase, blocking ergosterol synthesis. Lipophilic with high tissue concentrations.
Hepatotoxic: monitor liver enzymes. Requires acid pH for capsule absorption (give with food). Negative inotropic effect — avoid in animals with heart failure. CYP3A4 inhibitor.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Itraconazole dose ranges in cats, with cited source references: PO 5–10 mg/kg q12-24h; PO 5–10 mg/kg q24h; PO 5–10 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Itraconazole in cats: PO.
Cited course lengths for Itraconazole in cats include: Months; Weeks to months; 1 week on, 1 week off; 3-4 cycles. Duration depends on the indication — match it to the specific dose rule in the table above.
Itraconazole is indicated in cats for: Aspergillosis (sinonasal), Dermatophytosis, cryptococcosis, sporotrichosis, Ringworm (pulse therapy).
These are general warnings for Itraconazole across species; consult the cat dosing table above for species-specific guidance. Hepatotoxic: monitor liver enzymes. Requires acid pH for capsule absorption (give with food). Negative inotropic effect — avoid in animals with heart failure. CYP3A4 inhibitor.
Why a species-specific page? Itraconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.