Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
Fluconazole is dosed at 5 mg/kg PO q24h in rabbits, per Carpenter's Exotic Animal Formulary, 6th Ed, p.846, ref 163 = Miller JL, Schell WA, Wills EA, et al. In vitro and in vivo efficacies of the new triazole albaconazole against Cryptococcus neoformans. Antimicrob Agents Chemother. 2004;48:384-387; corroborated BSAVA Part B p.136 ('5 mg/kg p.o. q24h for cryptococcal meningitis') — Carpenter's Exotic Animal Formulary 6th ed, Table 10.2 (Antifungal Agents Used in Rabbits.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Fluconazole is used in rabbits for Cryptococcal meningitis. Routes documented in rabbits: PO. A typical adult rabbit weighs 1.00–5.00 kg. ExoticRx lists 1 cited dose rule for Fluconazole in rabbits, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Diflucan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 5 mg/kg | q24h | Weeks to months | Cryptococcal meningitis | Extrapolated | Carpenter's Exotic Animal Formulary, 6th Ed, p.846, ref 163 = Miller JL, Schell WA, Wills EA, et al. In vitro and in vivo efficacies of the new triazole albaconazole against Cryptococcus neoformans. Antimicrob Agents Chemother. 2004;48:384-387; corroborated BSAVA Part B p.136 ('5 mg/kg p.o. q24h for cryptococcal meningitis') — Carpenter's Exotic Animal Formulary 6th ed, Table 10.2 (Antifungal Agents Used in Rabbits.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 25–43 | IV | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.150 | 25-43 mg/kg i.v. infusion (slow) q12h; 37.5 mg/ kg p.o. q12h for Aspergillus keratitis; 5 mg/kg |
| 5 | PO | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.150 | 12h; 37.5 mg/ kg p.o. q12h for Aspergillus keratitis; 5 mg/kg p.o. q24h for cryptococcal meningitis |
| 38 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 10.2 | 38 mg/kg PO q12h |
| 5 |
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Inhibits fungal cytochrome P450 enzyme 14-alpha-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane.
Hepatotoxic: monitor liver enzymes during prolonged therapy. Drug interactions via CYP450 inhibition. Good CNS and ocular penetration.
Species-specific contraindications and adverse-reaction reports for rabbits may differ from canine / feline reference data — consult the primary citations listed with each rule.
Fluconazole dose range in rabbits, with cited source references: PO 5 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Fluconazole in rabbits: PO.
Cited course lengths for Fluconazole in rabbits include: Weeks to months. Duration depends on the indication — match it to the specific dose rule in the table above.
Fluconazole is indicated in rabbits for: Cryptococcal meningitis.
These are general warnings for Fluconazole across species; consult the rabbit dosing table above for species-specific guidance. Hepatotoxic: monitor liver enzymes during prolonged therapy. Drug interactions via CYP450 inhibition. Good CNS and ocular penetration.
Why a species-specific page? Fluconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in rabbits — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| PO |
| Carpenter's Exotic Animal Formulary, 6th edTable 10.2 |
| 5 mg/kg PO q24h |
| 37.5 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 10.9 | 37.5 mg/kg PO q12h |
| 80 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 10.2 | 80 mg/kg PO q24h × 21 days |
| 25–43 | IV | Carpenter's Exotic Animal Formulary, 6th edTable 10.2 | 25-43 mg/kg IV (slow) q12h,194 |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.