Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Amphotericin B is dosed at 0.5 mg/kg IV q48-72h in eastern box turtles, per 89. Frye FL. Reptile Clinician's Handbook. Malabar, FL: Krieger Publishing; 1994. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1404 (2026-08-01, PENDING REVIEW). Amphotericin B is used in eastern box turtles for systemic mycosis. Routes documented in eastern box turtles: IV. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 1 cited dose rule for Amphotericin B in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Fungizone, Abelcet
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IV | 0.5 mg/kg | q48-72h | systemic mycosis | Weak | 89. Frye FL. Reptile Clinician's Handbook. Malabar, FL: Krieger Publishing; 1994. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1404 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds ergosterol in fungal cell membranes, creating pores that cause leakage of intracellular contents and cell death.
Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amphotericin B dose range in eastern box turtles, with cited source references: IV 0.5 mg/kg q48-72h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amphotericin B in eastern box turtles: IV.
Amphotericin B is indicated in eastern box turtles for: systemic mycosis.
These are general warnings for Amphotericin B across species; consult the eastern box turtle dosing table above for species-specific guidance. Severely nephrotoxic (conventional form). Lipid formulations reduce nephrotoxicity but are expensive. Pre-hydrate with IV saline. Monitor BUN/creatinine and potassium. Fever, vomiting during infusion common. Reserved for systemic mycoses.
Why a species-specific page? Amphotericin B pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.