Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Griseofulvin is dosed at 15 mg/kg PO q72h in eastern box turtles, per 149. Jepson L. Lizards. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier; 2009:268-314. | 150. Jepson L. Snakes. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier; 2009:315-357. | 151. Jepson L. Turtles and tortoises. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier; 2009:358-411. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1404 — SOURCE EDITION: Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530 — PRINTED DETAIL MISSING FROM THIS RULE (retrieved 2026-08-19): *"Griseofulvin | 15 mg/kg PO q72h²²¹˒²²²˒²⁴³ | Most species"* — Carpenter's 6e, Table 4.3 (Antifungal Agents Used in Reptiles); identical row in Mader's 3e p.1194, Table 127.1. Missing printed caution, Mader's p.979: *"Griseofulvin has been shown to be teratogenic in pregnant animals of many species."*. Griseofulvin is used in eastern box turtles for dermatophytosis/mycosis. Routes documented in eastern box turtles: PO. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 1 cited dose rule for Griseofulvin in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Fulvicin, Grisovin
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 15 mg/kg | q72h | dermatophytosis/mycosis | Weak | 149. Jepson L. Lizards. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier; 2009:268-314. | 150. Jepson L. Snakes. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier; 2009:315-357. | 151. Jepson L. Turtles and tortoises. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier; 2009:358-411. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1404 — SOURCE EDITION: Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530 — PRINTED DETAIL MISSING FROM THIS RULE (retrieved 2026-08-19): *"Griseofulvin | 15 mg/kg PO q72h²²¹˒²²²˒²⁴³ | Most species"* — Carpenter's 6e, Table 4.3 (Antifungal Agents Used in Reptiles); identical row in Mader's 3e p.1194, Table 127.1. Missing printed caution, Mader's p.979: *"Griseofulvin has been shown to be teratogenic in pregnant animals of many species."* |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 15 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.3 | 15 mg/kg PO q72h,222,243 20-40 mg/kg PO q72h x Most 5 treatments |
| 20–40 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.3 | 15 mg/kg PO q72h,222,243 20-40 mg/kg PO q72h x Most 5 treatments |
| 15 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 15 mg/kg PO q72h149-151 20-40 mg/kg PO q72h × 5 treatm Most species ents281 Most species/dermatitis; limited success |
| 20–40 |
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits fungal mitosis by disrupting mitotic spindle microtubules. Deposits in keratin precursor cells, preventing fungal invasion of new growth.
TERATOGENIC — CONTRAINDICATED in pregnant animals. Bone marrow suppression (especially cats — monitor CBC). Give with fatty food (enhances absorption). Cats: FIV-positive at higher risk of toxicity. 4-8 week course minimum.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Griseofulvin dose range in eastern box turtles, with cited source references: PO 15 mg/kg q72h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Griseofulvin in eastern box turtles: PO.
Griseofulvin is indicated in eastern box turtles for: dermatophytosis/mycosis.
These are general warnings for Griseofulvin across species; consult the eastern box turtle dosing table above for species-specific guidance. TERATOGENIC — CONTRAINDICATED in pregnant animals. Bone marrow suppression (especially cats — monitor CBC). Give with fatty food (enhances absorption). Cats: FIV-positive at higher risk of toxicity. 4-8 week course minimum.
Why a species-specific page? Griseofulvin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| PO |
| Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 |
| 15 mg/kg PO q72h149-151 20-40 mg/kg PO q72h × 5 treatm Most species ents281 Most species/dermatitis; limited success |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.