Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Itraconazole is dosed at 5 mg/kg PO q24h in eastern box turtles, per 214. Martel A, Hellebuyck T, Van Waeyenberghe L. Treatment of infections with Nannizziopsis vriesii, an emergent reptilian dermatophytea. Proc Annu Conf Assoc Rept Amph Vet. 2009;69-70. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1405 (2026-08-01, PENDING REVIEW). Itraconazole is used in eastern box turtles for systemic/cutaneous mycosis. Routes documented in eastern box turtles: PO. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 1 cited dose rule for Itraconazole in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Sporanox, Itrafungol
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 5 mg/kg | q24h | systemic/cutaneous mycosis | Weak | 214. Martel A, Hellebuyck T, Van Waeyenberghe L. Treatment of infections with Nannizziopsis vriesii, an emergent reptilian dermatophytea. Proc Annu Conf Assoc Rept Amph Vet. 2009;69-70. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1405 (2026-08-01, PENDING REVIEW) |
Need the exact dose for your patient?
These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits fungal 14-alpha-demethylase, blocking ergosterol synthesis. Lipophilic with high tissue concentrations.
Hepatotoxic: monitor liver enzymes. Requires acid pH for capsule absorption (give with food). Negative inotropic effect — avoid in animals with heart failure. CYP3A4 inhibitor.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Itraconazole dose range in eastern box turtles, with cited source references: PO 5 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Itraconazole in eastern box turtles: PO.
Itraconazole is indicated in eastern box turtles for: systemic/cutaneous mycosis.
These are general warnings for Itraconazole across species; consult the eastern box turtle dosing table above for species-specific guidance. Hepatotoxic: monitor liver enzymes. Requires acid pH for capsule absorption (give with food). Negative inotropic effect — avoid in animals with heart failure. CYP3A4 inhibitor.
Why a species-specific page? Itraconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.