Reptile · Eublepharis macularius · typical adult weight 0.04–0.10 kg
Itraconazole is dosed at 23.5 mg/kg PO q24h in leopard geckos, per 147. Gamble KC, Alvarado TP, BennettCL. Itraconazole plasma and tissue concentrations in the spiny lizard (Sceloporus sp.) following once-daily dosing. J Zoo Wildl Med. 1997;28:89-93. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.222 (2026-08-01, PENDING REVIEW). Itraconazole is used in leopard geckos for Systemic/cutaneous fungal infection. Routes documented in leopard geckos: PO. A typical adult leopard gecko weighs 0.04–0.10 kg. ExoticRx lists 1 cited dose rule for Itraconazole in leopard geckos, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Sporanox, Itrafungol
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 23.5 mg/kg | q24h | Systemic/cutaneous fungal infection | Weak | 147. Gamble KC, Alvarado TP, BennettCL. Itraconazole plasma and tissue concentrations in the spiny lizard (Sceloporus sp.) following once-daily dosing. J Zoo Wildl Med. 1997;28:89-93. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.222 (2026-08-01, PENDING REVIEW) |
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Inhibits fungal 14-alpha-demethylase, blocking ergosterol synthesis. Lipophilic with high tissue concentrations.
Hepatotoxic: monitor liver enzymes. Requires acid pH for capsule absorption (give with food). Negative inotropic effect — avoid in animals with heart failure. CYP3A4 inhibitor.
Species-specific contraindications and adverse-reaction reports for leopard geckos may differ from canine / feline reference data — consult the primary citations listed with each rule.
Itraconazole dose range in leopard geckos, with cited source references: PO 23.5 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Itraconazole in leopard geckos: PO.
Itraconazole is indicated in leopard geckos for: Systemic/cutaneous fungal infection.
These are general warnings for Itraconazole across species; consult the leopard gecko dosing table above for species-specific guidance. Hepatotoxic: monitor liver enzymes. Requires acid pH for capsule absorption (give with food). Negative inotropic effect — avoid in animals with heart failure. CYP3A4 inhibitor.
Why a species-specific page? Itraconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in leopard geckos — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.